<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12283

Description pre-mRNA-processing protein 40A-like isoform X1
SequenceMPDEVKLARQSMKVDLVKGLGKERDSISHASDFGSISGVKTSPLSANGSPVSAQGAMSSPIAVAPVSNLPTIVASESSSLSGNISSLTIGAVEMQNSLEPASPAVATSEKNGTAVTLENSVATPVTSSEFPSAQDSVVYEDGVSLENTEEVKKDATVSETGSATPSEEKTVEPGPLVYESKAEAKSAFKILLESANIGSDWTWDQAMRAIINDRRYGALKSLGERKQAFNEYLSHKKKLEAEERRIKQKKAREDFRIMLEECKELAPSTRWSKAISIFEHDERFKAVERAKDREDLFEDYMEELEKKERARALEEQKRNRVEYLEFLKSCDFIKASSQWRKVQDRLEDDERCSCLEKIDRLEIFQEYIRDLEREEEEHRKLRMDEMRKAERKNRDEFRKLMEEHVAAGILNAKTNWRDYCIKVKDLPAYLAVSSNTSGPKAKDLFQDVFDELEKQYLDDKSRIRDAIRMAEIGLTSTWTLEDFKVAISKDISSPPISDTNLKFVFEELLERAREREEKEAKRRKRLADEFYELLHTSKEITASSKWEDCKSIFGDRIMGEESFLLEIFDKFISELKEKAKEKERKRQEDKARKEKERKDREKKKEKHRRDKDRGDKSRKERERTKKDGTDSEKADTYSFEEIKRLGSDRDKKHRKRHMSSFDDNENEKDHSRNSYRHDNDHKKSKQVDQHVWSSEVNSEGQHKKQKRDHRSGSLRDGDNEDHKDGEFGEDGEVR
Length734
PositionUnknown
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-1.106
Instability index45.83
Isoelectric point6.00
Molecular weight84802.55
Publications
PubMed=24807620

Function

Annotated function 
GO - Cellular Component
U1 snRNP	GO:0005685	IBA:GO_Central
U2-type prespliceosome	GO:0071004	IBA:GO_Central

GO - Biological Function
RNA binding	GO:0003723	IBA:GO_Central

GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro
mRNA splicing, via spliceosome	GO:0000398	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12283
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     453.53|      65|      65|     242|     306|       1
---------------------------------------------------------------------------
  167-  233 (61.56/29.06)	.........EEK.TV..EpgplvyesKAEAK..................SAFKIL.L.E...SANIG.SDWTWDQAMRAIIN.D.RRYGAL...K..SL.GERKQAFNEYL
  237-  301 (104.40/54.49)	KKL.EA...EER.RI..K........QKKAR..................EDFRIM.LEE...CKELA.PSTRWSKAISIFEH.D.ERFKAV...E..RA.KDREDLFEDYM
  302-  368 (83.74/42.23)	EEL.EK...KERaRAleE........QKRNR..................VEYLEF.LKS...CDFIK.ASSQWRKVQDRLED.D.ERCSCL...E..KI..DRLEIFQEYI
  369-  449 (60.57/28.47)	RDL.EReeeEHR.KL..R.mdemrkaERKNR..................DEFRKL.MEEhvaAGILN.AKTNW.RDYCIKVK.DlPAYLAVssnT..SG.PKAKDLFQDVF
  450-  531 (44.62/19.00)	DEL.EK.................qylDDKSRirdairmaeigltstwtlEDFKVA.I.....SKDISsPPISDTNLKFVFEElL.ERARER...EekEA.KRRKRLADEFY
  532-  572 (51.70/23.21)	E......................................................lLHT...SKEIT.ASSKWEDCKSIF...G.DRIMGE...E..SF...LLEIFDKFI
  573-  630 (46.93/20.38)	SELkEKakeKER.KR..Q........EDKAR.................kEKERKD.REK...KKE.K.H..RRDKD....RG.D.KSRKER...E..RTkKDGTD......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      79.56|      19|      19|     668|     686|       2
---------------------------------------------------------------------------
  649-  666 (23.95/10.48)	RD.KKHR.KRHMSSFDDNEN
  668-  686 (33.91/17.85)	KDHSRNS.YRHDNDHKKSKQ
  688-  705 (21.69/ 8.81)	DQHVWSSeVNSEGQHKK..Q
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.34|      37|      40|      48|      86|       3
---------------------------------------------------------------------------
   48-   86 (53.76/42.46)	GSpVSAQGAM..SSPiAVAPVSNLPTIVASESSSLSGNISS
   90-  128 (54.58/33.54)	GA.VEMQNSLepASP.AVATSEKNGTAVTLENSVATPVTSS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12283 with Med35 domain of Kingdom Viridiplantae
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