Description | mediator of RNA polymerase II transcription subunit 21-like isoform X3 |
Sequence | MSAAFVKAAKQFDALVAALPLSDGCEEAQLKRIAELQAESDVVGQELQKQLEAAGPLPGICLGGTTNRLHQASYGCIY |
Length | 78 |
Position | Middle |
Organism | Nicotiana tabacum (Common tobacco) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana. |
Aromaticity | 0.05 |
Grand average of hydropathy | 0.059 |
Instability index | 45.09 |
Isoelectric point | 4.87 |
Molecular weight | 8205.29 |
Publications | PubMed=24807620 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU366036 |
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule |
GO - Biological Function | |
GO - Biological Process |
Binary Interactions |
Repeats | >MDP12277 No repeats found No repeats found |
MoRF Sequence | Start | Stop |
1) EAQLKRIAELQAESD 2) LGGTTNRLHQASYGCIY 3) MSAAFVKAAKQFDALVA | 27 62 1 | 41 78 17 |
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