<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12271

Description pre-mRNA-processing protein 40A-like isoform X2
SequenceMASNPPPSGPQPLWPPSVGSTPPQGFGSSFPMQQGQPFASSISASPQYRPVGQTSNAGMPPGHHSQIPQFSQPMQQFPPRPNQPGHGILLSQAIQMPFIQSSMPQPQQVIPPLNSHMPGVSGAGNPFSSSYTVQSSSQMHVPSFPSGGQPWLSSGSQNTPVTAPTLLTNQQLSAIAPSVPAGTASPQNASDWQEYEAADGRRYYYNKITKQSSWEKPLELMTPLERADASTVWKEFTTADGRKYYYNKETKQSKWTIPEELKLARELAEKSAGQVVQTGASTTSGVQVTAAVTSTEQPSAVTPVSFTPSSTVSGVASSPVPVTSAVSDHASPLVVSGSSAIPAVTPAMPSSSGVSSPAVSGSTGSAALANASQTQMSGFENLSPQVSSSLSGASIQDIEEAKKGMAVAGKVNVVPAEEKTTEEEPFLYATKQEAKNAFKALLEFANVESDWTWEQTMRVIINDKRYGALKTLGERKQAFNEYLMQRKKQEAEERRHRQRKAKEEFTKMLEESKELISSTRWSKAVTMFEDDERFKAVEREADREDLFRNYLVDLQKKERAKAQEEYRQNRLEYRHFLETCGFIKVDTQWRKVQDLLEDDERCLRLEKIDRLDIFQEYIRDLEKEDEEQRKLQKEQLRRTERKNRDAFRKMMEEQITAGTLTAKTSWRDYCQMVKESVAYQAVASNTSGSTPKDLFEDVVEELEKQYHEDKIRVKDVVKSEKITISSTWTFEDFKATILEGIGSPSIHDVNLQLIFEDLIERAKEKEEKETKKRQRLAKDFTDKLSTIKEITASSSWEECKELVEDTSEFRAIGEETISRAVFEEYVAWLQEKAKEKERRREEEKAKKEKEKEEKEKRKDKERREKEREKEKERDKEKERGNERATKDEADSESMDVTDNYEPKEERKREKDRERKHRKRHHISNDEVTSDKDEKEEPERDKERKHRKRHHSSNDELASDKDEKEESKRSRRHSSDRKKSKKLAHSPESDGESRHKRHRRDHRDGSRRNGGGYEELEDGELGEDGES
Length1026
PositionUnknown
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-1.101
Instability index60.21
Isoelectric point6.06
Molecular weight116708.08
Publications
PubMed=24807620

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12271
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     175.60|      26|      26|     911|     936|       1
---------------------------------------------------------------------------
  504-  531 (23.88/ 7.52)	EFTKMLEESKE.......liSSTRWSKAVTMFEDD
  760-  778 (24.39/ 7.83)	ERAKEKEEK.E.........TKKR.QRLAK.....
  848-  865 (26.28/ 9.00)	E..KEKEEKEK.........RKDKERR......EK
  866-  890 (34.31/13.96)	EREKEK.ERDK.........EKERGNERATKDEAD
  926-  954 (37.35/15.84)	EVTSDKDEKEE......perDKERKHRKRHHSSND
  955-  989 (29.38/10.92)	ELASDKDEKEEskrsrrhssDRKKSKKLAHSPESD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     116.63|      23|      23|      61|      83|       2
---------------------------------------------------------------------------
    7-   36 (25.62/10.03)	PSGPQplwpPSVGSTPPQgFgsSF.P.MQQGQ
   56-   78 (43.38/21.74)	NAGMP....PGHHSQIPQ.F..SQ.P.MQQFP
   79-  103 (24.44/ 9.26)	PRPNQ....PGHGILLSQ.A..IQmPfIQSSM
  104-  123 (23.20/ 8.44)	PQPQQ..viPPLNSHMPG.V..SG.......A
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     136.37|      35|      38|     186|     220|       3
---------------------------------------------------------------------------
  186-  220 (72.36/45.49)	PQNASD....WQEYEAADGRRYYYNKITKQSSWEKPLEL
  223-  261 (64.01/39.35)	PLERADastvWKEFTTADGRKYYYNKETKQSKWTIPEEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     124.69|      23|      23|     578|     600|       4
---------------------------------------------------------------------------
  578-  599 (33.22/21.36)	......ETCGFIKVDTQWRKVQDLLEDD
  600-  625 (19.39/ 8.96)	ErclrlEKID..RLDIFQEYIRDLEKED
  637-  654 (24.31/13.38)	R.....RTER..KNRDAFRK...MMEEQ
  656-  676 (27.12/15.89)	.......TAGTLTAKTSWRDYCQMVKES
  786-  805 (20.65/10.09)	.......TIKEITASSSWEECKELVED.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.49|      20|      23|     331|     353|       5
---------------------------------------------------------------------------
  331-  351 (32.14/19.41)	SPlVVSGSSAIPAVTPAMPSS
  356-  375 (33.35/19.53)	SP.AVSGSTGSAALANASQTQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.61|      11|      21|     142|     162|       6
---------------------------------------------------------------------------
  142-  154 (16.82/10.97)	PSFPSGGQpwLSS
  164-  174 (17.79/18.17)	PTLLTNQQ..LSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     137.79|      39|      66|     464|     502|       7
---------------------------------------------------------------------------
  417-  465 (26.98/13.62)	........EE...KTTEEEPF..LYATKQEAKnafkallefanvesdwtwEQTMRVIIND.............................KR
  466-  533 (50.70/33.53)	YGALKTLGER...KQAFNEYL..MQRKKQEAE..................ERRHRQRKAKeeftkmleeskelisstrwskavtmfeddER
  534-  557 (23.35/10.57)	FKAVEREADR...EDLFRNYL..VDLQKK..............................................................
  809-  846 (36.76/21.83)	FRAI...GEEtisRAVFEEYVawLQEKAKE.K..................ERRREEEKAK...............................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.25|      24|      27|     271|     294|       9
---------------------------------------------------------------------------
  271-  294 (40.66/24.10)	SA.GQVVQTGASTTSGVQVTA.AVTS
  299-  324 (34.59/19.49)	SAvTPVSFTPSSTVSGVASSPvPVTS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.07|      21|      22|     713|     733|      12
---------------------------------------------------------------------------
  713-  733 (34.90/27.72)	VKDVVKSEKIT.ISSTWTFEDF
  737-  758 (30.18/22.87)	ILEGIGSPSIHdVNLQLIFEDL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12271 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KERRREEEKAKKEKEKEEKEKRKDKERREKEREKEKERDKEKERGNERATKDEADSESMDVTDNYEPKEERKREKDRERKHRKRHHISNDEVTSDKDEKEEPERDKERKHRKRHHSSNDELASDKDEKEESKRSRRHSSDRKKSKKLAHSPESDGESRHKRHRRDHRDGSRRNGGGYEELEDGELGEDGES
2) MASNPPPSGPQPLWPPSVGSTPPQGFGSSFPMQQGQPFASSISASPQYRPVGQTSNAGMPPGHHSQIPQFSQPMQQFPPRPNQPGHGILLSQAIQMPFIQSSMPQPQQVIPPLNSHMPGVSGAGNPFSSSYTVQSSSQMHVPSFPSGGQPWLSSGSQNTPVTAPTLLTNQQLSAIAPSVPAGTASPQNASDWQ
836
1
1026
193










Molecular Recognition Features






MoRF SequenceStartStop




1) GYEELEDGEL
2) ILLSQAIQ
3) KKSKKLAHS
4) SRHKRHRRDHRD
1011
88
977
992
1020
95
985
1003