<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12260

Description U-box domain-containing protein 35-like
SequenceMEEKGGVVTKVEGLSALNPLNSSTIAVAINGKRKSKYVVSWALNKFVPEGKVCFKLLHVRPCITGVPTPMGNSIPISQVRDDVVAAFRKDVEWQTSEKLHPYKMLCTKRKVLVEVLQLESDDIAKAIAEEVSKLNITKLVIGASSRSIFSRGQSLSSRISDSIPSFCTIYAVSRGKLLSIRPSNSEINASSWTEDSNTNFSISSSTGLSSSLLTEKSDLDSSSSYSQFRSPSLPMQRFQALSNINQNFPNRRAISNETVHHKNYSLDFGDSEDDVSYCPQRSFLSERNNLTSSFRSLVTEFYSTADDQASTSGAPTDLSLRNEADINFELEKLRTELRHTQGMYAVAQTEVLDASRKMNELQNRRLEEEIKLREISLKEEEAKDLVRKENEEYEAAKREADYVKDCAEREAAQRKEAELLALREAKEKDKLENALTDQAHQYQEFTWEEIVSSTSSFAENLKIGMGGYGTVYKCSLRHTTVAVKVLHSKGSDLTKQFQQELKILSKIRHQHLLILLGVCPDRGCLVYEFMENGSLEERLFRKHDTPPIPWFDRYRIAWEVASALAFLHNSKPDPIIHRDLKPANILLDRNFVSKIGDVGLSTMINSEAALSTIYRDTGPVGTLCYIDPEYQRTGMISPKSDVYAFGMVLLQLLTAKAAMGLPHIVETAIDKDSLTKVLDSKAGEWPLEETKKLAALALKCTEISRRDRPDLKDEILPALKRLKVVADKARDSASTTRPPPPTYYLCPLLKDVMEEPCVAADGYTYDRKAIETWLKENDISPMTNLPLPHKNLLPNYALLSAILDWKSRKDGNI
Length813
PositionTail
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.07
Grand average of hydropathy-0.422
Instability index43.23
Isoelectric point6.49
Molecular weight91312.83
Publications
PubMed=24807620

Function

Annotated function Functions as an E3 ubiquitin ligase. 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12260
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     148.43|      52|     325|     349|     407|       1
---------------------------------------------------------------------------
  349-  407 (73.35/90.18)	TEVLDAsrKMNELQnrrLEEEIKLREISLKEEEA..KDlvRKE..NEEYEAAKR...EADYVKDCA
  675-  733 (75.08/65.01)	TKVLDS..KAGEWP...LEETKKLAALALKCTEIsrRD..RPDlkDEILPALKRlkvVADKARDSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.73|      26|      31|     258|     288|       2
---------------------------------------------------------------------------
  258-  288 (41.06/34.46)	TVHHKNYSLDFGDSEDDvsycpQRSF......LSERN
  291-  322 (36.68/18.99)	TSSFRSLVTEFYSTADD.....QASTsgaptdLSLRN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.12|      20|      20|     193|     212|       4
---------------------------------------------------------------------------
  193-  212 (33.91/20.89)	TEDSNTNFSISSSTGLSSSL
  214-  233 (35.22/21.98)	TEKSDLDSSSSYSQFRSPSL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12260 with Med32 domain of Kingdom Viridiplantae
Unable to open file!