<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12241

Description U-box domain-containing protein 34-like isoform X3
SequenceMEDKRAQCEEIFIPFKILCKRKNVETLVLEGNNPATVLLKYVNDSGIKSLVLGSYSPNYFSRKLKGSSVPSIILKHAPECCDVYVVSSNKLMTNSLNPLLATEGDLPTINKQKSSASSASIDGVSHSRSSSLASSHLNFPAFVDGNSSNYVTPQHRPNRNLENVTTGLEAVKGCHSSTYSEQLDIQEEVERVRLELQTTLAMYNQTCEDLIHTRNKVQLFSSQYLEESGKVNAAKKREENLRKIAAEEKEKHIEAEKEVETARKLLSEETYERQIAELKALQQSLEKKKTVDALLSSDDRYRRLTREEIAVATDNFSESKIIGEGAYGKVYKGDLDHTPVAIKVLCSDASEKKEEFLREVEVLSQLHHPHIVLLLGACPENGCLVYEYMENGSLEDCILERNSKLFPWFFRFRILFEVACALAFLHNSKPEPIVHRDLKPGNILLDKNFVSKIGDVGLAKIISDIVPESVTEYRNSVLAGTLGYMDPEYQRTGTLRPKSDLYAFGIITLQLLAACRPNGLIMMFEDAINSNSLVDILDKSVPDWPLIEAEELARMALKCCNLRCRDRPDLETEVLPLLKRLSEFADMLTKVEKNLIQAPSPYLCPIVQEVMEDPQIAADGFTYEHRAIKLWLTRHSVSPVTKQLLQHQLVTPNRTLRLAIQEWRSQVTSFRTRP
Length674
PositionTail
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.07
Grand average of hydropathy-0.332
Instability index46.20
Isoelectric point6.05
Molecular weight76116.24
Publications
PubMed=24807620

Function

Annotated function Functions as an E3 ubiquitin ligase. 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12241
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.25|      20|      20|     234|     253|       1
---------------------------------------------------------------------------
  234-  253 (32.51/20.86)	AKKREENLRKIAAEEK.EKHI
  255-  275 (26.74/15.94)	AEKEVETARKLLSEETyERQI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.04|      16|      20|      14|      29|       2
---------------------------------------------------------------------------
   14-   29 (27.74/19.42)	PFKILCKRKN...VETLVL
   34-   52 (19.29/11.25)	PATVLLKYVNdsgIKSLVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     368.09|     122|     136|     315|     447|       3
---------------------------------------------------------------------------
  311-  440 (187.71/160.75)	VATDNFSeSKiIGEGAYGKVYKGDLDHTPVAIK..VLCSDASEKKEEFLR..EVEVLSQLHHPHIVL..LLGACPENG.CLVYE.YMENGSLEDcILERNSKLFPwFFRFRILFEVA...CALaflhNSKPEPIVHRDLKP
  444-  576 (180.38/118.23)	LLDKNFV.SK.IGDVGLAKIISDIVPESVTEYRnsVLAGTLGYMDPEYQRtgTLRPKSDLYAFGIITlqLLAACRPNGlIMMFEdAINSNSLVD.ILDKSVPDWP.LIEAEELARMAlkcCNL....RCRDRPDLETEVLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      31.05|      10|      20|     116|     125|       4
---------------------------------------------------------------------------
  116-  125 (18.07/11.91)	ASS.....ASIDGVS
  133-  147 (12.98/ 6.66)	ASShlnfpAFVDGNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.49|      16|      26|      61|      86|       5
---------------------------------------------------------------------------
   61-   79 (21.67/28.22)	SRKLKGSSVPSIIlkhAPE
   88-  103 (26.82/ 8.03)	SNKLMTNSLNPLL...ATE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.26|      21|      27|     148|     169|       6
---------------------------------------------------------------------------
  148-  169 (32.83/22.99)	SNYvTPQHRPNRNLENVTTGLE
  177-  197 (33.43/18.97)	STY.SEQLDIQEEVERVRLELQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12241 with Med32 domain of Kingdom Viridiplantae
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