<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12239

Description U-box domain-containing protein 34-like isoform X1
SequenceMSTFKKLQIDPQITRQMYNILHNIFFSLLVDHVVAYSFSVSKMKVNVDGDTGGSPSSTTETVTVAVAVKSAEGKSSQRAVKWAVEKLLAKAHRFVLIHVMPTITTIPTPSGESTLVNELEANVVKLYMEDKRAQCEEIFIPFKILCKRKNVETLVLEGNNPATVLLKYVNDSGIKSLVLGSYSPNYFSRKLKGSSVPSIILKHAPECCDVYVVSSNKLMTNSLNPLLATEGDLPTINKQKSSASSASIDGVSHSRSSSLASSHLNFPAFVDGNSSNYVTPQHRPNRNLENVTTGLEAVKGCHSSTYSEQLDIQEEVERVRLELQTTLAMYNQTCEDLIHTRNKVQLFSSQYLEESGKVNAAKKREENLRKIAAEEKEKHIEAEKEVETARKLLSEETYERQIAELKALQQSLEKKKTVDALLSSDDRYRRLTREEIAVATDNFSESKIIGEGAYGKVYKGDLDHTPVAIKVLCSDASEKKEEFLREVEVLSQLHHPHIVLLLGACPENGCLVYEYMENGSLEDCILERNSKLFPWFFRFRILFEVACALAFLHNSKPEPIVHRDLKPGNILLDKNFVSKIGDVGLAKIISDIVPESVTEYRNSVLAGTLGYMDPEYQRTGTLRPKSDLYAFGIITLQLLAACRPNGLIMMFEDAINSNSLVDILDKSVPDWPLIEAEELARMALKCCNLRCRDRPDLETEVLPLLKRLSEFADMLTKVEKNLIQAPSPYLCPIVQEVMEDPQIAADGFTYEHRAIKLWLTRHSVSPVTKQLLQHQLVTPNRTLRLAIQEWRSQVTSFRTRP
Length801
PositionTail
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.07
Grand average of hydropathy-0.262
Instability index46.00
Isoelectric point6.41
Molecular weight90034.22
Publications
PubMed=24807620

Function

Annotated function Functions as an E3 ubiquitin ligase. 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12239
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.25|      20|      20|     361|     380|       2
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  361-  380 (32.51/19.70)	AKKREENLRKIAAEEK.EKHI
  382-  402 (26.74/15.03)	AEKEVETARKLLSEETyERQI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     368.09|     122|     136|     442|     574|       3
---------------------------------------------------------------------------
  438-  567 (187.71/152.08)	VATDNFSeSKiIGEGAYGKVYKGDLDHTPVAIK..VLCSDASEKKEEFLR..EVEVLSQLHHPHIVL..LLGACPENG.CLVYE.YMENGSLEDcILERNSKLFPwFFRFRILFEVA...CALaflhNSKPEPIVHRDLKP
  571-  703 (180.38/111.86)	LLDKNFV.SK.IGDVGLAKIISDIVPESVTEYRnsVLAGTLGYMDPEYQRtgTLRPKSDLYAFGIITlqLLAACRPNGlIMMFEdAINSNSLVD.ILDKSVPDWP.LIEAEELARMAlkcCNL....RCRDRPDLETEVLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.04|      16|      20|     141|     156|       4
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  141-  156 (27.74/17.82)	PFKILCKRKN...VETLVL
  161-  179 (19.29/10.28)	PATVLLKYVNdsgIKSLVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     107.31|      26|      27|     270|     296|       5
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  248-  267 (30.62/17.39)	IDG.VS.......HSRSSSLASSHLNFP
  270-  296 (40.81/30.48)	VDG.NSSNYvTPQHRPNRNLENVTTGLE
  298-  324 (35.88/21.67)	VKGcHSSTY.SEQLDIQEEVERVRLELQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12239 with Med32 domain of Kingdom Viridiplantae
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