<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12235

Description U-box domain-containing protein 52-like isoform X1
SequenceMWPPPPGVHGERMHTPNKLIAVAIDKDRGSQIALKWTVDHLLARGQTVLLIHVKLKQSANSSGQSPTTCLDLDYPMDYLLSDLTETCDTESNQISDEAGSGNSELDPQTKELFLPFRVFCTRKDVQCHDVVLDDTDVVKAIVEYVNRTGIEVLILGATTRGGLLRFKVKDIPGGILKGVPDFCTVHVISKSGKIASTRAASRPAPFVHPLRHQLMQPASTKFAPFEGSTPSAASARGPYSGGPKPVCDPPPSTLQSDTMNIKSPFTHRKGPNGKPYEISLPDTDISYVSSGRPSIDNIYSSFSDGYDGGGPTPPRLSGFSDFETQSFDSTQFGRRSVDTLTPPELSLSSIESDRPSISQGPVDDMEAEMRRLKQELKQTMELYSTACREALTAKQKAMELQRWKQEEQRRLEEARLAEEAALALAEKEKAKSRAAIEHAEAAQRLAELEAQKRISAEMKALKEAEEKNKILNKLTNSDFRYRKYTIEEIESATDYFAQTRKIGEGGYGPVYKCYLDHTPVAVKVLRPDAAHGRQQFQQEVEVLSCIRHPNMVLLLGACPEYGCLVYEYMSNGSLEDRLFHRGKTPPLSWQQRFRIAAEIATGLLFLHQSKPEPLVHRDLKPGNILLDRNFVSKISDVGLARLVPPSVADTVTQYRMTSTAGTFCYIDPEYQQTGMLGVKSDVYSLGIIFLQILTAKPPMGLTHYVDRAIEKGTFNEMLDPAIPDWPVDEALSLAKLSLQCSELRRKDRPDLGKVVLPQLERLRALAEDHTCPSLMYNSNISPNHSQISLSRDNLSYPNTMPSSYESSRSQ
Length810
PositionTail
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.07
Grand average of hydropathy-0.459
Instability index49.28
Isoelectric point6.30
Molecular weight90030.22
Publications
PubMed=24807620

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP12235
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      69.10|      20|      23|     419|     440|       1
---------------------------------------------------------------------------
  406-  430 (25.38/20.75)	EEQRRLEEARlaeeaALALAEKEKA
  431-  450 (24.84/16.43)	KSRAAIEHAE....aAQRLAELE.A
  451-  468 (18.89/10.68)	QKRISAE......mkALKEAE.EKN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.89|      11|      30|     312|     323|       5
---------------------------------------------------------------------------
  312-  323 (19.27/13.98)	TPPRLSgFSDFE
  341-  351 (20.63/10.00)	TPPELS.LSSIE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      31.59|      15|      30|     199|     220|       6
---------------------------------------------------------------------------
  209-  248 ( 7.60/14.45)	PlrhqlmqPASTkfapfegstpsAASargpysgGPKPVCD
  249-  267 (23.98/11.48)	P.......PPST.......lqsdTMN.......IKSPFTH
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP12235 with Med32 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) FEGSTPSAASARGPYSGGPKPVCDPPPSTLQSDTMNIKSPFTHRKGPNGKPYEISLPDTDISY
2) TQFGRRSVDTLTPPELSLSSIESDRPSISQGPVDDMEAEMRRLKQE
225
330
287
375

Molecular Recognition Features

MoRF SequenceStartStop
NANANA