<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12227

Description mediator of RNA polymerase II transcription subunit 25-like isoform X3
SequenceMVVFTVHGSHGACLVRRSGWTTDIDMFFQWLSAIPFSGGGFNDAAVAESLAEALTMFSSLNGSQTQQNVDGQRHCILIAASNPYPLPTPVYHPHMQNVEQSGNIEAHTANRLSDAETVAKEFPQCSVSLSVICPKQLPKLRAIYNAGKRDPQAADPPIDTSKNPNFLVLISENFIEACAAFNRTGMEISALNQILVEMDMSSVAPVSAPAATFDPAGSVMSQQPISAGSIPSATVNMEPTTVTSVTGPALPHIPTARPTSQLVASLQSASPISVSEEVVPNNEIVNETKPILSGMTQPLRSFSGAAANARILNDVAQAQALVGGTSIGLQSMGGTPILSNMIPGGISSSIPAAPTVLSSGQLAVTSMSGLVPLAGTGQIAQNSVSASSVSIAPSMSGNSNLCVSQLLSNIQGGVSAVMHQNVLSGTGAGMPFGTGTLMSTPRMTQPGHPGMQPLGRNNSTEANIPLSQRQTSATLSSAQSNYVKVWEGDLSGQRQGEPVLITRLQGFRIASASKSLAADWPQTMQIVRLITQEHLNNDVRRLIGKSEIVVFWAMDQHVFLSQLQEKKFCAVIQLPSQAMILSVSDKTCRLIGMLFPENTVVFKPQKLNQQLEAQHPQLEQLLLQQSLPLLQQQRALSRLQQQQPLQQLQQQQHLMPLKRKRNIPLQQQPKIPKLHRQQSPQIQQQQQIPQMQQTEQQQPIIGTCVNQASTGGPRRAQLMSQGQASSRGLPNVP
Length733
PositionUnknown
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.04
Grand average of hydropathy-0.161
Instability index59.08
Isoelectric point8.70
Molecular weight78487.70
Publications
PubMed=24807620

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12227
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      85.13|      24|      27|     645|     671|       1
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  619-  645 (23.51/ 8.91)	EQLLLQQSL.PL.......LQQQRAL.........srlqqqqpL
  646-  680 (34.41/26.09)	QQLQQQQHLMPLKRKRnipLQQQPKI.........pklhrqqsP
  681-  719 (27.21/11.63)	Q.IQQQQQIPQMQQTE....QQQPIIgtcvnqastggprraqlM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      97.17|      24|      27|     281|     304|       2
---------------------------------------------------------------------------
  239-  271 (26.61/11.59)	PTTVTS...VTGPALphiptarptSQLVASLQSASP
  281-  304 (41.94/22.57)	NNEIVN...ETKPIL.........SGMTQPLRSFSG
  308-  334 (28.63/13.04)	NARILNdvaQAQALV.........GGTSIGLQSMGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.77|      20|      27|     343|     369|       3
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  343-  364 (29.38/15.19)	PGGISSSIPA.APtvLSSGQLAV
  453-  473 (26.38/15.62)	PLGRNNSTEAnIP..LSQRQTSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      65.81|      22|      27|     366|     389|       4
---------------------------------------------------------------------------
  366-  380 (19.74/ 6.89)	.................SMSGLVPLAGTGQIA
  381-  408 (26.45/18.78)	QNSVSAssV....siapSMSGNSNLCVSQLLS
  411-  435 (19.62/ 7.41)	QGGVSA..VmhqnvlsgTGAGM.PF.GTG...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.98|      17|      46|     541|     562|       5
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  541-  562 (26.46/35.05)	RLIGkseivVFWAMDQHVFLSQ
  589-  605 (31.52/25.48)	RLIG.....MLFPENTVVFKPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     189.58|      60|      70|      82|     151|       6
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   82-  151 (90.19/66.44)	NPyPLPTPvYHPHMQNVEQSGNIEAHTA.NRlSDAETVAKEFPQCSVSLSVICPKQLPklraiynAGKRDP
  155-  215 (99.38/50.02)	DP.PIDTS.KNPNFLVLISENFIEACAAfNR.TGMEISALNQILVEMDMSSVAPVSAP.......AATFDP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12227 with Med25 domain of Kingdom Viridiplantae
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