<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12226

Description mediator of RNA polymerase II transcription subunit 25-like isoform X2
SequenceMMEKQLIVAVEGTAAVGPFWQTIISDYLDKMIRSFTKLEPIEKKPSAGNWQLAMVVFTVHGSHGACLVRRSGWTTDIDMFFQWLSAIPFSGGGFNDAAVAESLAEALTMFSSLNGSQTQQNVDGQRHCILIAASNPYPLPTPVYHPHMQNVEQSGNIEAHTANRLSDAETVAKEFPQCSVSLSVICPKQLPKLRAIYNAGKRDPQAADPPIDTSKNPNFLVLISENFIEACAAFNRTGMEISALNQILVEMDMSSVAPVSAPAATFDPAVMSQQPISAGSIPSATVNMEPTTVTSVTGPALPHIPTARPTSQLVASLQSASPISVSEEVVPNNEIVNETKPILSGMTQPLRSFSGAAANARILNDVAQAQALVGGTSIGLQSMGGTPILSNMIPGGISSSIPAAPTVLSSGQLAVTSMSGLVPLAGTGQIAQNSVSASSVSIAPSMSGNSNLCVSQLLSNIQGGVSAVMHQNVLSGTGAGMPFGTGTLMSTPRMTQPGHPGMQPLGRNNSTEANIPLSQRQTSATLSSAQSNYVKVWEGDLSGQRQGEPVLITRLQGFRIASASKSLAADWPQTMQIVRLITQEHLNNDVRRLIGKSEIVVFWAMDQHVFLSQLQEKKFCAVIQLPSQAMILSVSDKTCRLIGMLFPENTVVFKPQKLNQQLEAQHPQLEQLLLQQSLPLLQQQRALSRLQQQQPLQQLQQQQHLMPLKRKRNIPLQQQPKIPKLHRQQSPQIQQQQQIPQMQQTEQQQPIIGTCVNQASTGGPRRAQLMSQGQASSRGLPNVP
Length784
PositionUnknown
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.04
Grand average of hydropathy-0.152
Instability index57.54
Isoelectric point8.66
Molecular weight84307.52
Publications
PubMed=24807620

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12226
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      85.13|      24|      27|     696|     722|       1
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  670-  696 (23.51/ 6.26)	EQLLLQQSL.PL.......LQQQRAL.........srlqqqqpL
  697-  731 (34.41/18.60)	QQLQQQQHLMPLKRKRnipLQQQPKI.........pklhrqqsP
  732-  770 (27.21/ 8.22)	Q.IQQQQQIPQMQQTE....QQQPIIgtcvnqastggprraqlM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.39|      24|      27|     332|     355|       2
---------------------------------------------------------------------------
  332-  355 (43.05/24.75)	NNEIVN...ETKPILSGMTQPLRSFSG
  359-  385 (31.34/15.89)	NARILNdvaQAQALVGGTSIGLQSMGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      31.09|      12|      27|     394|     420|       3
---------------------------------------------------------------------------
  394-  405 (22.71/ 6.39)	P.........GGIS.SSIPAAP
  423-  444 ( 8.38/ 8.22)	PlagtgqiaqNSVSaSSVSIAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      33.88|      11|      49|     592|     602|       4
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  592-  602 (17.72/ 9.72)	RLIGKSEIVVF
  613-  623 (16.16/ 8.24)	QLQEKKFCAVI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     121.44|      35|      36|     249|     284|       5
---------------------------------------------------------------------------
  204-  261 (34.89/15.09)	PQAA.DPPIdTSKNPnflvlISE..NFIEAcAafnrtgmeisalnqilVEMDMS.SVAPVSA
  262-  298 (51.61/30.13)	PAATfDPAV.MSQQP.....ISA..GSIPS.A...............tVNMEPT.TVTSVTG
  299-  331 (34.94/15.12)	PAL...PHI.PTARP.....TSQlvASLQS.A................SPISVSeEVVP...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     158.53|      35|      66|     447|     482|       6
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  447-  482 (54.41/35.58)	SGNSNLCVSQLLSNIQGGVSAVMHQNvLSGTGAGMP
  485-  516 (52.96/30.26)	TG.TLMSTPRMTQPGHPGMQPLGRNN...STEANIP
  518-  549 (51.16/28.96)	SQRQ...TSATLSSAQSNYVKVWEGD.LSGQRQGEP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12226 with Med25 domain of Kingdom Viridiplantae
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