<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12221

Description probable mediator of RNA polymerase II transcription subunit 26b
SequenceMAKSFGTLEKWRDYFRTANSDIFDIIEHAIMVAATDCPKEFKLRRDKIAEMLFTCKVTRCFGCDKVELAVPLANDDEGKNKNKSEFGGGFEAKESKANSSIDHHIELNVNQVSNYSYGDAEALTEEIEEETQTLGEVLRIKDIIDNSQHESAELYECLRRLQLMALSVETLKATEIGKSVNALRKHSSKDIRHLSRTLIEDWKILVDEWVNATAAFTGTESTPESMKVSVVDQEEEGLPSPPLDDLAFFAAQTTSMELSQFFDGMDDDGNPRNSGEFNENRGNGRKSSLDDQNNPVRKKQSADFFDAAPKERKSEQQKKQETVIKKQTPVMRPNKPCGGDSGPGRPIKPVSEQKLKMSEMNFQQKSDQGTVHKRPVPTQQNKLRRSDEDAVQVKLEATKRKLQERYQEAENAKRQRTIQVMELHDIPKQGISNQGLGLKNPHMRPGNNNRHWANGRR
Length457
PositionUnknown
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-0.921
Instability index51.51
Isoelectric point6.28
Molecular weight51796.46
Publications
PubMed=24807620

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12221
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     103.79|      23|      26|     265|     290|       1
---------------------------------------------------------------------------
   75-  100 (32.14/12.16)	DDEGKN...KNKSEFGggfEAKESKANSS
  266-  288 (42.87/23.80)	DDDGNP...RNSGEFN...ENRGNGRKSS
  290-  314 (28.78/ 9.92)	DDQNNPvrkKQSADFF...DAAPKERKS.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.29|      19|      26|     340|     359|       2
---------------------------------------------------------------------------
  340-  359 (30.89/25.52)	DSGP..GRPIkPVSEQKLKMSE
  367-  387 (30.40/19.75)	DQGTvhKRPV.PTQQNKLRRSD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.84|      19|      29|     215|     238|       4
---------------------------------------------------------------------------
  215-  238 (22.91/29.77)	AFTGTESTpeSMKVSvvdQEEEGL
  247-  265 (34.93/23.48)	AFFAAQTT..SMELS...QFFDGM
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12221 with Med26 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SQFFDGMDDDGNPRNSGEFNENRGNGRKSSLDDQNNPVRKKQSADFFDAAPKERKSEQQKKQETVIKKQTPVMRPNKPCGGDSGPGRPIKPVSEQKLKMSEMNFQQKSDQGTVHKRPVPTQQNKLRRSDEDAVQVKLEATKRKLQERYQEAENAKRQRTIQVMELHDIPKQGISNQGLGLKNPHMRPGNNNRHWANGRR
259
457










Molecular Recognition Features






MoRF SequenceStartStop




1) PGRPIKPVSEQKLKMSEMNF
343
362