<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12215

Description U-box domain-containing protein 35-like
SequenceMEEKDGVVTKVEGLSALNPLNSSTIAVAINGKKKSKYVVSWALDKFVPEGKVCFKLLHVRPCITGVPTPMGNSIPISQVRDDVVAAFRKDVEWQTSEKLHPYKMLCTRLKVQVEVVQLESDDIVEAIAHEVSKLNIIKLVIGASSWSIFSRGQSLSSRISDSIPSFCTIYAVSRGKLLSIRPSNSEINGSSWTEDSNTSCSISTSTGHSSSLLTEKSDLDSSSSYSQFRSPSLPMQRFQALSNINQNFPHRRAISNEIIHHKNYSLDFGDSEDDVSSCPQRSFLRERNNLASSFRSLVTDFYTMADDQASTSGAPTDLSLRNEVDINFELEKLRTELRHTQGMYAVAQTEVLDASRKMNELQNRRLEEEIKLQEISLKEEEAKDLVRKEKEEYKAAKREADYVKDCAEREAALRKEAELLALREAKEKDKLENALTDQAHQYQEFTWEEIVSSTSSFAENLKIGVGAYGTVYKCSLRHTTVAVKVLHSKSKGSDLTKQFQQELKILSKIRHPHLLILLGVCPDRGCLVYEFMENGSLEERLFRKHDTPPIPWFDRYRIAWEVASALAFLHNSKPDPIIHRDLKPANILLDRNFVSKIGDVGLSTMINSDAALSTIYRDTGPVGTLCYIDPEYQRTGMISPKSDVYAFGMVLLQLLTAKAPMGLPHIVETAIDKDSLTKVLDSKAGEWPLEETKKLAALALKCTEICRRDRPDLKEEILPALEKLKEVANKARDSASTTRPPPPTYYLCPLLKDVMEEPCVAADGYTYDRKAIETWLKDNDISPMTNLPLPHKNLLPNYALLSAILDWKSRKAGNI
Length815
PositionTail
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.07
Grand average of hydropathy-0.394
Instability index41.31
Isoelectric point6.37
Molecular weight91554.33
Publications
PubMed=24807620

Function

Annotated function Functions as an E3 ubiquitin ligase. 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12215
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     104.88|      36|      39|     284|     322|       1
---------------------------------------------------------------------------
  284-  322 (49.92/46.91)	LRERNNLASSFRSlVTDFYTMAddQASTSGAPTDLS.LRN
  327-  363 (54.96/38.74)	NFELEKLRTELRH.TQGMYAVA..QTEVLDASRKMNeLQN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.89|      39|     325|     366|     407|       2
---------------------------------------------------------------------------
  366-  407 (58.69/44.59)	LEEEIKLQEISLKEEEakdLVRKE....KEEYKAA....KREADYVKDCA
  689-  735 (53.20/32.63)	LEETKKLAALALKCTE...ICRRDrpdlKEEILPAleklKEVANKARDSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.34|      20|      20|     193|     212|       3
---------------------------------------------------------------------------
  193-  212 (35.96/20.01)	TEDSNTSCSISTSTGHSSSL
  214-  233 (32.39/17.35)	TEKSDLDSSSSYSQFRSPSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.25|      19|      38|      81|     104|       5
---------------------------------------------------------------------------
   81-  104 (28.20/35.46)	DDVVAAFRKDVewqtsEKLHPYKM
  121-  139 (31.05/22.16)	DDIVEAIAHEV.....SKLNIIKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.48|      13|      21|     150|     162|       6
---------------------------------------------------------------------------
  150-  162 (23.51/13.94)	SRGQSLSSRISDS
  173-  185 (23.97/14.35)	SRGKLLSIRPSNS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12215 with Med32 domain of Kingdom Viridiplantae
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