<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12195

Description uncharacterized protein LOC107776844 isoform X2
SequenceMDSADWRTQLLPDSRQRIVNNITETLKRHLSVTREGGVQELKKIAAGFEEKIYTAATSQQDYLRKISLKMLTMETKSQNPMTNSSNAASSGQNAHDPGTAPAGAAVGVLDAADWRIQLLPDSRQSIVNKITETLKRHLSVTRQEGVQELMKIAVGFEEKIYTAATSQPDYQRKISLKMLTMETKSQNPMTNSANAASSGQNAHDPGTTPAGTAAGAMDAVDWRTQLLPDSRQRIVNKITETLKRHLPVTGEEGVQELKKIAVRFEEKIYTAAISQPDYLRKISLKMLTMETKSQHPMTNSTNAASSGQNALGPDSCQEREITQGSMKRKRENSGDNVEEHNDQILPTFTCEICTEVVPITMKFNNFHSCNHSFCSKCIERHVEVKIQLRIADIQCPYVDCGKLLDPLVCRTMIPLSIFEEWCDLLCRQAHLGFEKCYCPYQDCGEVIVKECEDVVGKSECPNCRRLICFQCGLPWNVCEENGCSKVNDTLFKELVEQKQWTKCPSCNMYVERIAGCNHMQCRCNFCFCYKCGKSPTAQRRWCRCK
Length545
PositionTail
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-0.510
Instability index41.14
Isoelectric point8.11
Molecular weight61329.56
Publications
PubMed=24807620

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
metal ion binding	GO:0046872	IEA:UniProtKB-KW
transcription coactivator activity	GO:0003713	IEA:InterPro
transferase activity	GO:0016740	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12195
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     113.92|      11|      15|      78|      88|       1
---------------------------------------------------------------------------
   78-   88 (23.09/10.59)	QNPMTNSSNAA
   95-  105 (22.24/10.00)	HDPGTAPAGAA
  186-  196 (23.86/11.14)	QNPMTNSANAA
  203-  213 (21.58/ 9.54)	HDPGTTPAGTA
  294-  304 (23.14/10.64)	QHPMTNSTNAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     165.13|      17|      20|      41|      57|       2
---------------------------------------------------------------------------
   41-   57 (32.98/19.78)	LKKIAAGFEEKIYTAAT
   63-   75 (26.34/14.63)	LRKISL....KMLTMET
  149-  165 (33.56/20.23)	LMKIAVGFEEKIYTAAT
  172-  183 (19.96/ 9.69)	.RKISL....KMLTMET
  257-  272 (25.94/14.32)	LKKIAVRFEEKIYTAA.
  279-  291 (26.34/14.63)	LRKISL....KMLTMET
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     254.42|      55|     107|       1|     107|       3
---------------------------------------------------------------------------
    1-   94 (82.05/50.13)	...MDSADWRTQLLPDSRQRIVNNITETLKRHLSVTREGGVQElkkiaagfeekiytaatSQQDYlrkislkmltmetKSqnpmtnssnaaSSGQNA
  106-  202 (84.85/52.07)	VGvLDAADWRIQLLPDSRQSIVNKITETLKRHLSVTRQEGVQElmkiavgfeekiytaatSQPDYqrkislkmltmetKSqnpmtnsanaaSSGQNA
  214-  310 (87.52/53.91)	AGaMDAVDWRTQLLPDSRQRIVNKITETLKRHLPVTGEEGVQElkkiavrfeekiytaaiSQPDYlrkislkmltmetKSqhpmtnstnaaSSGQNA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.00|      20|      58|     452|     472|       4
---------------------------------------------------------------------------
  411-  432 (25.10/ 7.85)	TMIPLSIFEEWCDLLCRQAhlG
  453-  472 (38.91/18.14)	DVVGKSECPNCRRLICFQC..G
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      82.47|      10|      40|     395|     404|       5
---------------------------------------------------------------------------
  369-  378 (22.22/10.66)	CNHSFCSKCI
  395-  404 (20.91/ 9.62)	CPYVDCGKLL
  438-  447 (21.32/ 9.95)	CPYQDCGEVI
  523-  531 (18.02/ 7.35)	CNFCFCYKC.
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12195 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) METKSQHPMTNSTNAASSGQNALGPDSCQEREITQGSMKRKRENSGDNVE
2) METKSQNPMTNSSNAASSGQNAHDPGTAPAGA
3) RKISLKMLTMETKSQNPMTNSANAASSGQNAHDPGTTPAGTAAGAMDAVDW
289
73
172
338
104
222










Molecular Recognition Features






MoRF SequenceStartStop




1) LRKISLKML
63
71