<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12194

Description uncharacterized protein LOC107776844 isoform X3
SequenceMDSADWRTQLLPDSRQRIVNNITETLKRHLSVTREGGVQELKKIAAGFEEKIYTAATSQQDYLRKISLKMLTMETKSQNPMTNSSNAASSGQNAHDPGNAYFGSEGTAPAGAAVGVLDAADWRIQLLPDSRQSIVNKIQEGVQELMKIAVGFEEKIYTAATSQPDYQRKISLKMLTMETKSQNPMTNSANAASSGQNAHDPGTTPAGTAAGAMDAVDWRTQLLPDSRQRIVNKITETLKRHLPVTGEEGVQELKKIAVRFEEKIYTAAISQPDYLRKISLKMLTMETKSQHPMTNSTNAASSGQNALGPDSCQEREITQGSMKRKRENSGDNVEEHNDQILPTFTCEICTEVVPITMKFNNFHSCNHSFCSKCIERHVEVKIQLRIADIQCPYVDCGKLLDPLVCRTMIPLSIFEEWCDLLCRQAHLGFEKCYCPYQDCGEVIVKECEDVVGKSECPNCRRLICFQCGLPWNVCEENGCSKVNDTLFKELVEQKQWTKCPSCNMYVERIAGCNHMQCRCNFCFCYKCGKSPTAQRRWCRCK
Length541
PositionTail
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-0.504
Instability index40.22
Isoelectric point7.63
Molecular weight60732.75
Publications
PubMed=24807620

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
metal ion binding	GO:0046872	IEA:UniProtKB-KW
transcription coactivator activity	GO:0003713	IEA:InterPro
transferase activity	GO:0016740	IEA:UniProtKB-KW
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP12194
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     570.36|      99|     107|      37|     143|       1
---------------------------------------------------------------------------
    1-   98 (177.42/108.95)	..........MDSADWRTQLLPDSRQRIVNNITETLKrhlsvtregGV.QELKKIAAGFEEKIYTAATSQQDYLRKISLKMLTMETKSQNPMTNSSNAASSGQNAHDPG
  107-  202 (197.58/135.13)	TAPAGAAVGVLDAADWRIQLLPDSRQSIVNKIQEG.............vQELMKIAVGFEEKIYTAATSQPDYQRKISLKMLTMETKSQNPMTNSANAASSGQNAHDPG
  203-  309 (195.35/118.19)	TTPAGTAAGAMDAVDWRTQLLPDSRQRIVNKITETLKrhlpvtgeeGV.QELKKIAVRFEEKIYTAAISQPDYLRKISLKMLTMETKSQHPMTNSTNAASSGQNALGP.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      89.65|      20|      58|     448|     468|       2
---------------------------------------------------------------------------
  351-  373 (23.63/ 6.95)	EVVPITmkfnNFHSCNHSFCSKC.
  407-  426 (28.45/10.62)	TMIPLS....IFEEWCDLLCRQAH
  449-  468 (37.57/17.59)	DVVGKS....ECPNCRRLICFQCG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.70|      10|      40|     391|     400|       3
---------------------------------------------------------------------------
  391-  400 (22.53/14.56)	CPYVDCGKLL
  434-  443 (23.17/15.19)	CPYQDCGEVI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.16|      16|      18|     502|     519|       4
---------------------------------------------------------------------------
  502-  519 (31.36/23.22)	CNMYveRIAGCNHMQ...CRC
  522-  540 (30.80/16.61)	CFCY..KCGKSPTAQrrwCRC
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP12194 with Med15 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) METKSQHPMTNSTNAASSGQNALGPDSCQEREITQGSMKRKRENSGDNVE
2) METKSQNPMTNSSNAASSGQNAHDPGNAYFGSE
3) RKISLKMLTMETKSQNPMTNSANAASSGQNAHDPGTTPAGTAAG
285
73
168
334
105
211

Molecular Recognition Features

MoRF SequenceStartStop
1) RKISLKML
64
71