<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12193

Description uncharacterized protein LOC107776844 isoform X1
SequenceMDSADWRTQLLPDSRQRIVNNITETLKRHLSVTREGGVQELKKIAAGFEEKIYTAATSQQDYLRKISLKMLTMETKSQNPMTNSSNAASSGQNAHDPGNAYFGSEGTAPAGAAVGVLDAADWRIQLLPDSRQSIVNKITETLKRHLSVTRQEGVQELMKIAVGFEEKIYTAATSQPDYQRKISLKMLTMETKSQNPMTNSANAASSGQNAHDPGTTPAGTAAGAMDAVDWRTQLLPDSRQRIVNKITETLKRHLPVTGEEGVQELKKIAVRFEEKIYTAAISQPDYLRKISLKMLTMETKSQHPMTNSTNAASSGQNALGPDSCQEREITQGSMKRKRENSGDNVEEHNDQILPTFTCEICTEVVPITMKFNNFHSCNHSFCSKCIERHVEVKIQLRIADIQCPYVDCGKLLDPLVCRTMIPLSIFEEWCDLLCRQAHLGFEKCYCPYQDCGEVIVKECEDVVGKSECPNCRRLICFQCGLPWNVCEENGCSKVNDTLFKELVEQKQWTKCPSCNMYVERIAGCNHMQCRCNFCFCYKCGKSPTAQRRWCRCK
Length553
PositionTail
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-0.512
Instability index40.89
Isoelectric point7.99
Molecular weight62155.38
Publications
PubMed=24807620

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
chromatin DNA binding	GO:0031490	IBA:GO_Central
metal ion binding	GO:0046872	IEA:UniProtKB-KW
transcription coactivator activity	GO:0003713	IEA:InterPro
transferase activity	GO:0016740	IEA:UniProtKB-KW
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP12193
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     656.51|     107|     107|     107|     213|       1
---------------------------------------------------------------------------
    1-   97 (202.04/120.45)	..........MDSADWRTQLLPDSRQRIVNNITETLKRHLSVTREGGVQELKKIAAGFEEKIYTAATSQQDYLRKISLKMLTMETKSQNPMTNSSNAASSGQNAHDP
  107-  213 (227.46/136.41)	TAPAGAAVGVLDAADWRIQLLPDSRQSIVNKITETLKRHLSVTRQEGVQELMKIAVGFEEKIYTAATSQPDYQRKISLKMLTMETKSQNPMTNSANAASSGQNAHDP
  215-  321 (227.01/136.12)	TTPAGTAAGAMDAVDWRTQLLPDSRQRIVNKITETLKRHLPVTGEEGVQELKKIAVRFEEKIYTAAISQPDYLRKISLKMLTMETKSQHPMTNSTNAASSGQNALGP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.00|      20|      58|     460|     480|       2
---------------------------------------------------------------------------
  419-  440 (25.10/ 6.40)	TMIPLSIFEEWCDLLCRQAhlG
  461-  480 (38.91/14.96)	DVVGKSECPNCRRLICFQC..G
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      82.47|      10|      40|     403|     412|       3
---------------------------------------------------------------------------
  377-  386 (22.22/ 9.31)	CNHSFCSKCI
  403-  412 (20.91/ 8.38)	CPYVDCGKLL
  446-  455 (21.32/ 8.68)	CPYQDCGEVI
  531-  539 (18.02/ 6.34)	CNFCFCYKC.
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP12193 with Med15 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) METKSQHPMTNSTNAASSGQNALGPDSCQEREITQGSMKRKRENSGDNVE
2) METKSQNPMTNSSNAASSGQNAHDPGNAYFGSE
3) RKISLKMLTMETKSQNPMTNSANAASSGQNAHDPGTTPAGTAAGAMDAVDW
297
73
180
346
105
230

Molecular Recognition Features

MoRF SequenceStartStop
1) RKISLKML
64
71