<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12169

Description mediator of RNA polymerase II transcription subunit 30-like
SequenceMEEKGGTMANPKTIQELAVEGQKHLEDTIEAAHQILSAMNDELCNPTLWSTTPNTAATTSANAVMSNGQQQHHSNGGGDVSSDNSSSSSASAQQHLDIGGGALDESRLRYKSSIACLRSVLTAISNSQKAKALEAASASGSLSAADQAEIEQLEERASTLKKELVDKNKHLKLLIDQLRYLLSDLSTWQSPCST
Length194
PositionHead
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.02
Grand average of hydropathy-0.509
Instability index46.56
Isoelectric point5.19
Molecular weight20623.54
Publications
PubMed=24807620

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP12169
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.60|      21|      22|      70|      90|       1
---------------------------------------------------------------------------
   70-   90 (39.13/24.44)	QQHHSNGGG..DVSSDNSSSSSA
   93-  115 (32.48/19.20)	QQHLDIGGGalDESRLRYKSSIA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.83|      22|     144|      15|      37|       2
---------------------------------------------------------------------------
   15-   37 (32.62/29.47)	QELaVEGQKHLEDTIEAAHQILS
  162-  183 (36.21/27.31)	KEL.VDKNKHLKLLIDQLRYLLS
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP12169 with Med30 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) MEEKGGTMANPKTIQELAVEGQKHLEDTIEAA
2) PTLWSTTPNTAATTSANAVMSNGQQQHHSNGGGDVSSDNSSSSSASAQQHLDI
1
46
32
98

Molecular Recognition Features

MoRF SequenceStartStop
1) QQHLDI
2) SRLRYKS
93
106
98
112