<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12160

Description U-box domain-containing protein 33-like isoform X2
SequenceMELLTPSPTPLTPSSNSLSGFSSMATYRRGFYRTSQIITPQTREIVEEQNEPKVYIAVGKSVNKNVALVQWACKTFGNSEICIFYVLEPSPYIPTLLGRLPATQANAEVVSAFRDAEREEARKLLSRYLNVCCKSKVKASVAIVEAHFVLKGILDFVNKHNIRKLIIGAIPDCVKVKKSSQKASFAAAYFPSFCEIFFVYKGKLVWTRQPPDCSSFIGPISANTRAVVADACSLRSRSLTSCKREVILSPERARSSSSRDLLSSGIKSLIFEEGISSDTGLWPKNFSSTSRSNPIIFPSLSISTSPSTGSSCASSAEQMESPDVELESLYKQLEEVCIEFESSRNEAIAEMLKRKKLEAEAVEAMRKVKAFESAHAHEVKLRKEAEVALENILLEKEKLLKEREEKTSELRKAMRNIALLDSRTQEADQRCEEIAGELTLIHSSIATLRQEKRKLLQQNTEAMNWINRWKNRGKDGVLSASGEWSASPALLEFSLSELQTATCNFSESFRIGQGGYADVFKGELADKTVVIKQLHPHNMQQQSQFFEQVEILAKLRHPQLVTLLGVCPEAWCLVYEYIPGRSLQDRLFCKNISPMNWKMRARIISEIASALLFLHSSYPEQIAHGDLRPENMLLDSTDSCKICDTGISSLIPQQTLRCPSFGRQSEPKGLFSYTDPEFHITGALTTKSDIYSFGLIILQILTGRTLAGLLSEVRRAVSCAELESLLDSSAGEWSTYVSRRLAELALQCCEVNSRDRPELTPTLVMELENLHVLEERSVPSFFVCPIRQDIMLDPQIAADGFTYEGEAIQGWLESGHDTSPMTNLKLSHLELTPNHSLRLAIQDWLCNLEFLT
Length852
PositionTail
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.07
Grand average of hydropathy-0.208
Instability index52.65
Isoelectric point6.29
Molecular weight95334.09
Publications
PubMed=24807620

Function

Annotated function Functions as an E3 ubiquitin ligase.
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP12160
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.48|      28|      39|     136|     173|       1
---------------------------------------------------------------------------
  136-  173 (41.82/45.62)	KVKASVA......IVEAHFVLKGILDFVNKHnirkliigaiPDC
  180-  213 (48.66/32.06)	SQKASFAaayfpsFCEIFFVYKGKLVWTRQP..........PDC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     189.86|      45|      47|     350|     394|       2
---------------------------------------------------------------------------
  350-  394 (68.25/41.12)	EM.LK.RKKLEAEAVEAMRKVKAFESAHAHEVKLRKEAEVALENILL
  398-  441 (59.06/34.67)	KL.LKeREEKTSELRKAMRNIALLDS.RTQEADQRCE.EIAGELTLI
  447-  491 (62.54/37.11)	TLrQE.KRKLLQQNTEAMNWINRWKNRGKDGV.LSASGEWSASPALL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     176.98|      57|     371|     248|     314|       3
---------------------------------------------------------------------------
  248-  314 (89.65/72.73)	LSPERArssssrdLLSSGIKSLIFEEGISSdtgLWPKN...FSSTSR.SNPI.IF....PSLSISTSPSTGSSCAS
  627-  692 (87.33/50.93)	LRPENM.......LLDSTDSCKICDTGISS...LIPQQtlrCPSFGRqSEPKgLFsytdPEFHITGALTTKSDIYS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.39|      10|      39|      51|      60|       5
---------------------------------------------------------------------------
   51-   60 (18.46/10.30)	EPKVYIA..VGK
   88-   99 (15.92/ 7.95)	EPSPYIPtlLGR
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP12160 with Med32 domain of Kingdom Viridiplantae

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