<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12159

Description U-box domain-containing protein 33-like isoform X1
SequenceMELLTPSPTPLTPSSNSLSGFSSMATYRRGFYRTSQIITPQTREIVEEQNEPKVYIAVGKSVNKNVALVQWACKTFGNSEICIFYVLEPSPYIPTLLGRLPATQANAEVVSAFRDAEREEARKLLSRYLNVCCKSKVKASVAIVEAHFVLKGILDFVNKHNIRKLIIGAIPDFCSLHRSEISSYGSCLLYPSLPFIYSCVKVKKSSQKASFAAAYFPSFCEIFFVYKGKLVWTRQPPDCSSFIGPISANTRAVVADACSLRSRSLTSCKREVILSPERARSSSSRDLLSSGIKSLIFEEGISSDTGLWPKNFSSTSRSNPIIFPSLSISTSPSTGSSCASSAEQMESPDVELESLYKQLEEVCIEFESSRNEAIAEMLKRKKLEAEAVEAMRKVKAFESAHAHEVKLRKEAEVALENILLEKEKLLKEREEKTSELRKAMRNIALLDSRTQEADQRCEEIAGELTLIHSSIATLRQEKRKLLQQNTEAMNWINRWKNRGKDGVLSASGEWSASPALLEFSLSELQTATCNFSESFRIGQGGYADVFKGELADKTVVIKQLHPHNMQQQSQFFEQVEILAKLRHPQLVTLLGVCPEAWCLVYEYIPGRSLQDRLFCKNISPMNWKMRARIISEIASALLFLHSSYPEQIAHGDLRPENMLLDSTDSCKICDTGISSLIPQQTLRCPSFGRQSEPKGLFSYTDPEFHITGALTTKSDIYSFGLIILQILTGRTLAGLLSEVRRAVSCAELESLLDSSAGEWSTYVSRRLAELALQCCEVNSRDRPELTPTLVMELENLHVLEERSVPSFFVCPIRQDIMLDPQIAADGFTYEGEAIQGWLESGHDTSPMTNLKLSHLELTPNHSLRLAIQDWLCNLEFLT
Length878
PositionTail
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.08
Grand average of hydropathy-0.190
Instability index54.13
Isoelectric point6.32
Molecular weight98286.45
Publications
PubMed=24807620

Function

Annotated function Functions as an E3 ubiquitin ligase. 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12159
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     124.73|      43|      69|     342|     386|       1
---------------------------------------------------------------------------
  342-  386 (62.14/46.24)	AE.QMESPDVELESLYKQLEEVCIEFESSRNEaIAeMLKRKKLEAE
  411-  454 (62.59/38.00)	AEvALENILLEKEKLLKEREEKTSELRKAMRN.IA.LLDSRTQEAD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.76|      13|      16|     148|     160|       2
---------------------------------------------------------------------------
  148-  160 (22.68/10.74)	FVLKGILDFVNKH
  165-  177 (24.08/11.72)	LIIGAIPDFCSLH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     107.87|      26|     130|     466|     491|       3
---------------------------------------------------------------------------
  466-  491 (46.16/27.42)	LIHSS....IA..TLRQEKRKLLQQNTEAMNW
  599-  623 (44.50/26.19)	LVYEY....IP..G.RSLQDRLFCKNISPMNW
  639-  664 (17.22/ 6.04)	FLHSSypeqIAhgDLRPE..NMLLDSTD....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     132.26|      42|     371|     296|     340|       4
---------------------------------------------------------------------------
  296-  340 (72.23/49.72)	IFEEGISSdtgLWPKN...FSSTSR.SNPI.IF....PSLSISTSPSTGSSCAS
  668-  718 (60.03/33.72)	ICDTGISS...LIPQQtlrCPSFGRqSEPKgLFsytdPEFHITGALTTKSDIYS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      94.22|      24|     161|     103|     126|       6
---------------------------------------------------------------------------
  103-  126 (36.87/23.92)	TQANAEVVSAFRDAEREEARKLLS
  246-  262 (19.33/ 8.89)	.......ISANTRAVVADACSLRS
  266-  289 (38.03/24.91)	TSCKREVILSPERARSSSSRDLLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.37|      22|      28|     190|     211|       8
---------------------------------------------------------------------------
  190-  211 (40.21/25.59)	YPSLP...FIYSC..VKVKKSSQKASF
  216-  242 (36.16/22.27)	FPSFCeifFVYKGklVWTRQPPDCSSF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.39|      10|      36|      51|      60|      13
---------------------------------------------------------------------------
   51-   60 (18.46/10.86)	EPKVYIA..VGK
   88-   99 (15.92/ 8.36)	EPSPYIPtlLGR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12159 with Med32 domain of Kingdom Viridiplantae
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