<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12158

Description mediator of RNA polymerase II transcription subunit 16
SequenceMADSGMEMGKRVSFDPFDLPSDVRTLARIVYSAHGGEIAVAFLRGGVHVFSGPSFTPVDNYHIDVGSAISAPAFSSTSCCSASVWHDTSRDCTILKIIRVLPPAVPSNQGKANSANWERAIAERFWWSLLVGVDWWDAVGCTQSAAEDGIVALNSVIAVLDADFHSLPSTQHRQQYGPSLDRIKCRLLEGTNAQEVRAMVLDMQARLLLDMLGKGIESALTNPSALVPEPWQASSETLFGIDPEAMAVEPALVPSIQAYVDAILDLASHFITRLRRYASFCRTLASHAVTAGTGGSRSMVTSPTPSVTSPATSQGAQGGTASSTGNTQMQAWVQGAIAKISSTADSVPSSAPNPITGPSTFMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLHFCFFFRGTQLPRFMGAAQRNADSSMQKPQPSIPGKAEDSNSGAKPTPGGQVGTGAKGSEEGPSKRSRIGSGNAGQGYTYEEVRVLFLILMDLCRRTAGLVHPLPVSQVGSSNIQVRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELHPPAEEWHRRNMFGGPWSDSEDIGGVDDNSKLSPSRDLTECSSSENCDVSYGAHGLWPRKRRMSERDAAFGLNTSVGLGAYLGIMGSRRDVVTAVWKTGLEGVWYKCIRCLRQTSAFTSPGGNPSATQNEKEVWWISRWAYGCPMCGGTWVRVV
Length708
PositionTail
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.07
Grand average of hydropathy-0.169
Instability index43.23
Isoelectric point6.63
Molecular weight76113.25
Publications
PubMed=24807620

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12158
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.39|      16|      17|     289|     304|       1
---------------------------------------------------------------------------
  289-  304 (28.29/11.59)	VT..AGTGGSRSMVTSPT
  307-  324 (22.10/ 7.79)	VTspATSQGAQGGTASST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.58|      25|     114|     254|     281|       3
---------------------------------------------------------------------------
  254-  281 (37.51/34.77)	PSIQAyVDAILDlaSHFITRLRRYASFC
  372-  396 (51.07/33.39)	PGTPA.VRLIGD..CHFLHRLCQLLHFC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     165.00|      47|     563|      84|     141|       4
---------------------------------------------------------------------------
   84-  141 (74.41/61.06)	VWHdTSRDCTILKIIRVL..PPAVPSNQGKANSANWERAIaerfWWsllvgVDWWdAVGC
  649-  697 (90.59/46.95)	VWK.TGLEGVWYKCIRCLrqTSAFTSPGGNPSATQNEKEV....WW.....ISRW.AYGC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.87|      13|      18|     439|     451|       5
---------------------------------------------------------------------------
  439-  451 (24.58/13.04)	PTPGGQVGTGAKG
  456-  468 (23.29/11.96)	PSKRSRIGSGNAG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.77|      17|      18|     170|     187|       6
---------------------------------------------------------------------------
  170-  187 (27.05/24.26)	TQHRQQYGPSLDrIKCRL
  191-  207 (27.72/18.96)	TNAQEVRAMVLD.MQARL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12158 with Med16 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GAAQRNADSSMQKPQPSIPGKAEDSNSGAKPTPGGQVGTGAKGSEEGPSKRSRIGSGN
2) GTGGSRSMVTSPTPSVTSPATSQGAQGGTASSTGNT
409
292
466
327










Molecular Recognition Features






MoRF SequenceStartStop




NANANA