<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12155

Description mediator of RNA polymerase II transcription subunit 23
SequenceMATLWLAILLPSYVSVEALKFRILLCKLLLQHLTSRNPTTLTKPGNTILVFEILNYRFLSLYRYQGKSKTLMYDVTKMISTLKGKRGDHRIFRLAENLCMNLILSLRDFFSVKREGKGPTEFTETLNRITIVTLAIIIKTRGIGEFDQLLYLQTMLEQILATSQHTWSEKTLRYFPSILRDALSGRMDKRGLAIQAWQQAETTVINQCTQLLSPSADPTYVMTYINHSFPQHRQYLCAGAWILMHGHPENINCTNLGRVLREFSPEEVTANIYTMVDVLLHHIHLELQRGHPLQDLMLKACGNLSVFIWTHELLPPDILLLALIDRDDNPHALRIVINLLDSKELQQRVKLYLINRGPPEHWLSSGPFKRVELQKALGNYLSWKERYPTFFDDIAARLLPIIPLIIYRLIENDAMDAADRALQVYSTFLHCYPLNFTFVRDILAYFYGHLPGKLILRILNILDIKKIPFSESFPQHINSSNAAMCPPLDYFATLLLGLVNHVIPALNNSSKCAAMGDFANNSTRAPHGKIQATSQPGPTNSSEGQKPYYQMQDPGTFTQLTLETAVIELLSLPVSPSQIVSSLVQIVVHIQPTLVQSSNGLHGAPGSSGQGSILPTSPSGGSSDSLGATRTTPSVSGMNTSNFVSRSGYTCQQLSCLLIQACGLLLAQLPPEFHVQLYVEAARIIKESWWLTDAKRSVGELESAVSYALLDPTWAAQDNTSTAIGNVVALLHAFFCNLPQEWLEGTHLIIKHLRPVTSVAVLRIAFRIMGPLLPRLANAHTLFSKTLSLLLNILVDVFGRNSQLSTPIEATEITDLIDFLHHVIHYEGQGGPVQASSKPRSEILALFGRAAENLRPDVQHLLSHLNTDARSSIYAATHPKIVQTP
Length885
PositionTail
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.08
Grand average of hydropathy0.039
Instability index44.52
Isoelectric point8.41
Molecular weight98936.37
Publications
PubMed=24807620

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
transcription regulator complex	GO:0005667	IBA:GO_Central

GO - Biological Function
GO - Biological Process
positive regulation of gene expression	GO:0010628	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12155
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.17|      19|      43|     192|     211|       1
---------------------------------------------------------------------------
  192-  211 (30.20/25.03)	LAIQAW..QQAETTVINqCTQL
  236-  256 (34.96/23.73)	LCAGAWilMHGHPENIN.CTNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.04|      12|     378|     293|     304|       2
---------------------------------------------------------------------------
  293-  304 (22.60/15.32)	LQDLMLKACGNL
  654-  665 (22.45/15.16)	LSCLLIQACGLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     244.48|      85|     170|     313|     411|       3
---------------------------------------------------------------------------
  313-  411 (126.86/105.20)	LLPP.D...ILLLALIDrddnpHalriVINLLDSKELQQRVKLYLIN..RGPPEHWLSS...GPFKRVELQKAlgnYLSWKEryPTFFDDIAARL.......LPIIP.LIIYRLIE
  484-  585 (117.61/68.29)	MCPPlDyfaTLLLGLVN.....H....VIPALNNSSKCAAMGDFANNstRAPHGKIQATsqpGPTNSSEGQKP...YYQMQD..PGTFTQLTLETaviellsLPVSPsQIVSSLVQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     118.13|      34|     518|     257|     292|       7
---------------------------------------------------------------------------
  257-  292 (54.57/42.64)	GRVLREFSPEEVTaNIYTMVDVLLHHIHLELQrGHP
  799-  832 (63.56/40.28)	GRNSQLSTPIEAT.EITDLIDFLHHVIHYEGQ.GGP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.82|      15|     520|     145|     167|       8
---------------------------------------------------------------------------
  145-  160 (20.48/26.40)	EfDQLLYLQTMLEQIL
  169-  183 (25.34/ 7.90)	E.KTLRYFPSILRDAL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12155 with Med23 domain of Kingdom Viridiplantae
Unable to open file!