<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12154

Description mediator of RNA polymerase II transcription subunit 12-like
SequenceVYQIGQQIVMGLMDCMRQTGGAAQEGDPTLVSSAISAIVCNIGQVIAKIPDLTASNNHLSFSSTSASLHFARCILRIHVICLCILKEALGERQSRVFEVALATETSSALAPVFAPGKAPRSQFQLSPELNDSNPPSDILNNSSRVALGRAAKISAAVSALVIGAILQGVASLERMVSLFRLKDGLDVVHFMRSMRSNSNGNARSVGTLKADSLAEVSVHWFRVLVGNCRTVSDGFIVDLLGEASILALCRMQRMLPLNLVFPPAFSMFAFVLWRPLILNASSGTRDEVQQLHHSLLLAFGDVIKHLPFREVCLRDTHSLYDLIAADTVDSDFASLLEASGVDLRTKASAFVPLRARLFLNALIDCRIPQPIVKQDDGNQVGVQGESKFHGAENETKLLDKLVYILDTLQPAKFHWQWIELRLLLNEQAVIEKLEGHDLSLVEALRALSPNTDKASVSENESNIIEMILTRLLVRPDAAPLFSEVVHLLGRSLEDSMLLQAKWFLGGHDVLFGRKSVRQRLINIAVSKGLSTRAQYWKPWGWCPSNSDPTTSKGEKFKSEVSSIEEGEVVDEGTTLKRPVKGSGHTVDVEGFLVRQQHVTERALVDLILPCLDQASDDSRSTFASDMIKQMNHIEQQINAVTREASKPAGTIASGIESPTTKSSRKGTRGSSPGLARRASGPAETVPPSPVALRASLSLRLQFILRLFPIIYADREPSGRNMRYMLASVILRTLGSRIVHEDASHFFNQAYSSKRELDSLVEASSTASVVMSLESLFDRLLLLLHGLLSSHQPRWLKGKSSSKSSSESSKDYSAFEREGAENLQNELDRMQLPETVRWRIQSAMPILFPSVRWSISCQPPSVAPAALSSLLPSNPISVLHSSNGLNQTQRTPVSLLRTAMSVSGKAKHVSSQQENDLEVDPWILLEDGAGSSQSSSNSTLVGGSDNANLKASNWLKGTVRVRRTDLTYIGAVDDDS
Length975
PositionKinase
OrganismNicotiana tabacum (Common tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-0.078
Instability index47.82
Isoelectric point7.41
Molecular weight106576.50
Publications
PubMed=24807620

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12154
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.12|      10|      37|     642|     651|       1
---------------------------------------------------------------------------
  642-  651 (18.51/ 9.65)	REASKPAGTI
  676-  685 (18.61/ 9.74)	RRASGPAETV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     143.13|      42|     134|     692|     767|       2
---------------------------------------------------------------------------
  319-  360 (68.43/25.59)	LYDLIAADTVDSDFASLLEASGVDLRTKASAFVPLRARLFLN
  706-  747 (74.70/56.28)	LFPIIYADREPSGRNMRYMLASVILRTLGSRIVHEDASHFFN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      32.94|      13|     289|     205|     236|       5
---------------------------------------------------------------------------
  199-  218 (16.38/25.06)	NGNAR.svgtlkaDSLAEVSV
  225-  245 (16.56/12.85)	VGNCRtvsdgfivDLLGEASI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.50|      15|      15|      97|     111|       8
---------------------------------------------------------------------------
   97-  111 (23.26/13.36)	FEVALATETSSALAP
  113-  127 (27.23/16.90)	FAPGKAPRSQFQLSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      66.43|      15|      16|     556|     570|       9
---------------------------------------------------------------------------
  556-  570 (23.13/18.45)	FKSEVSSIEEGEVVD
  575-  587 (21.06/15.98)	LKRPVKG..SGHTVD
  591-  605 (22.24/17.39)	FLVRQQHVTERALVD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     140.59|      45|     119|      26|      72|      10
---------------------------------------------------------------------------
   26-   72 (68.65/56.32)	GDPTLVSSAISAIVcnIGQVIAKIPDLTASNNHLSFSSTSASLHFAR
  148-  192 (71.94/50.88)	GRAAKISAAVSALV..IGAILQGVASLERMVSLFRLKDGLDVVHFMR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12154 with Med12 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IEQQINAVTREASKPAGTIASGIESPTTKSSRKGTRGSSPGLARRASGPAETVP
633
686










Molecular Recognition Features






MoRF SequenceStartStop




1) EVDPWILLED
2) IGAVD
917
968
926
972