<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12131

Description mediator of RNA polymerase II transcription subunit 25 isoform X1
SequenceMSEFQLIVVVESTAAMGPYWETVLMDYLDKMIRSFGVNDSTGQKSSAPNVEFALITYNTHGCYSGCLVQRTGWTRDPDVFFLWLSSIPFNGGGFNDAAIAEGLSEALMMFPNSQSGGPNQQSVDMHKHCILIAASNPYPLQTPVYVPRPQNLEQSETIDSDSGNRLYDAEAVAKAFPQFSISLSVICPKQLPKIKAIYNAGKRSNRAADPPLEAKTPHFLILISEGFREARIALSRSGITSLASNQSPVKVDTVPVTPVTGAPPTSLPSVNGSIVNRQPVPAGNVAPPATVKVEQVPLTSVVSGPSFPHNSSVPRANSTSQGVPSLQTSSPSSVSQDIVTNNENTQDTKPTVSMLQPLRPVNPTQSILNNLSQARQVMSSAALSGGTSMGLPSMGQTPVAMHMSNMISSGMTSSVPAAQNVFSSGQSGITSITSSGPLSVPAQVGQNPGLGSLTSNTSNLSSTSNIGISQPLGNLQGAVSMGQQAPGMSQGNLSGPQMVQGGVPMSQSAMSGLGPSVVSSGNGTMIPTPGMSQQQSGMPPIVNNGAANMPLSQQTSGGMQSSQSKYVKVWEGSLSGQRQGQPVFITKLEGYRNSSASETLAANWPSVMQIVRLISQDHMNNKQYVGKADFLVFRAMNPHGFLVQLQEKKLCAVIQLPSQTLLLSVSDKAFRLIGMLFPGDMVVFKPQLSSQQQQQMQQQHQQMQSQQQHLPQLQQQQPLPHMQQQQLPQMQLPQMQQQQQQLQQQQQLPQMQQQQQQLQQQQLPQMQQQQQQLPQMQQQQQQLPQLQQQQQLPQLQQQQQQQQLSQLQQQQHPQIQQQQQLPQLQQQIPQLQPQQQQIVGAGMGQAYVQGPGRSQLVSQGQVSSQGTTNIGGGGFMS
Length877
PositionUnknown
OrganismVigna radiata var. radiata (Mung bean) (Phaseolus aureus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Vigna.
Aromaticity0.04
Grand average of hydropathy-0.437
Instability index70.79
Isoelectric point8.82
Molecular weight94663.83
Publications
PubMed=25384727

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12131
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     289.60|      43|      43|     712|     754|       1
---------------------------------------------------------------------------
  680-  709 (46.35/ 9.16)	DMVVFKPQLSSQQQQ.......QMQQQ...............HQQMQsQQQ.......H
  712-  754 (94.54/26.66)	QLQQQQPLPHMQQQQLPQMQLPQMQQQ...............QQQLQ.QQQQLPQMQQQ
  755-  777 (38.06/ 6.15)	............QQQLQQQQLPQMQQQ......................QQQLPQMQ..
  778-  810 (63.51/15.39)	..QQQQQLPQLQQQQ....QLPQLQQQ...................Q.QQQQLSQLQQQ
  814-  861 (47.15/ 9.45)	QIQQQQQLPQL.QQQIPQLQ.PQ.QQQivgagmgqayvqgpgRSQLV.SQGQ.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     120.46|      23|      23|     515|     537|       2
---------------------------------------------------------------------------
  404-  428 (23.68/ 6.40)	SNMISSGMTSSVPAAQnvFSSGQSG
  476-  494 (25.91/ 7.88)	QGAVSMGQ....QAPG..MSQGNLS
  515-  537 (41.34/18.12)	PSVVSSGNGTMIPTPG..MSQQQSG
  539-  557 (29.54/10.29)	PPIVNNGAANM...P...LSQQTSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     211.71|      57|      58|     254|     310|       3
---------------------------------------------------------------------------
  188-  251 (47.80/17.39)	..............PKQLP.KIKaiynaGKRS....NRAADPPLEAKTPhflilisegfreARIALSRSGITSLASNQSPVKV
  254-  310 (101.56/44.62)	VPVTPVT..GAP..PTSLP.SVN.....GSIV....NRQPVPAGNVAPP............ATVKVEQVPLTSVVSGPSFPHN
  313-  370 (62.35/24.76)	VPRANSTsqGVPslQTSSPsSVS.....QDIVtnneNTQ.....DTKP..............TVSMLQ.PLRPVNPTQSILNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.53|      20|      48|     378|     398|       4
---------------------------------------------------------------------------
  379-  401 (28.34/15.88)	SSAALSGGTSmGLPSMGQTPvaM
  449-  468 (27.20/10.62)	GLGSLTSNTS.NLSSTSNIG..I
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12131 with Med25 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PLGNLQGAVSMGQQAPGMSQGNLSGPQMVQGGVPMSQSAMSGLGPSVVSSGNGTMIPTPGMSQQQSGMPPIVNNGAANMPLSQQTSGG
2) QQMQQQHQQMQSQQQHLPQLQQQQPLPHMQQQQLPQM
3) SNQSPVKVDTVPVTPVTGAPPTSLPSVNGSIVNRQPVPAGNVAPPATVKVEQVPLTSVVSGPSFPHNSSVPRANSTSQGVPSLQTSSPSSVSQDIVTNNENTQDTKPTVSMLQPLRPVNPTQSILNNLSQARQVMSSAALSGGTSMGLPSMGQTPVAMHMSNMISSGMTSSVPAAQNVFSSGQSGITSITSSGPLSVPAQVGQNPGLGSLTSNTSNLSSTSNIGIS
471
694
244
558
730
469










Molecular Recognition Features






MoRF SequenceStartStop




NANANA