<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12129

Description mediator of RNA polymerase II transcription subunit 23
SequenceMDQSQNQRPATSTTPSRSLQFHPARGTILDLFNLYLGIGRNSRHKPEESLREPPNKTQKRVHALNRELPPPNEQFILDFEQLQSQFPDQDQLRSVTEAILISLVVQCSGHGPRADFLLFVLRGLCGIGCINWDSFLQSLLSSVSSAELPVGQLSQAVPTVSLSSLSQTGMLPPPSTIANSSNFQSSNPASPLTSVHAIGSPAQSTIEPLSCAAMSPVKSSDISSAGQQSKLRGGSSVRNNDISNSSLRQLCCKIILIGLEFSLKPVTYAEIFNHMLNWLLNWDQRQQGINESDVIKSWRPDKSVIAWLHSCLDVIWLLVDEGKCRVPFYELLRSDLQFIENIPDDEALFTLILEIHRRRDMMAMHMQMLDQHLHCPTFGTHRILTQTTPTVSGEAVTHMRLSPITYSSVLGEPLHGEDIASSIQKGSLDWERAVRCIRHALRTTPSPDWWRRVLVLAPCYRLSSQMPTAGAVFSSEMICEATIDRIVELLKMTNSEINCWQDWLVFSDIFYFLIKSGCIDFVDFVDKLVSRLTEGDHHILKTNHVTWLLAQIIRIEQVMNALNTDPRKVETTRKILSFHREDKSSDPNNSQSILLDFVSSCQNLRIWSLNSSTREYLNNEQLQKGKQIDEWWRQASKGDRMMDYMNMDERSIGMFWVVTYTMAQPACETVMNWLNSAGVADLLPGTNLQTAERLMATREVSPLPMSLLAGFSINLCVKLSYQMEDSLFSGQVIPSIAMVETYTRLLLLAPHSLFRSHFNHLVQRNPSLLSKPGVTLLVLEILNYRLLPLYRYQGKSKALMYDVTKIISAIKGKRGDHRVFRLAENLCLNLIFSLRDFFLVKREGKGPTDFTETLNRVTVITLAILIKTRGIADAEHLLYLQNMLEQIMATSHHTWSEKTLHHFPSVLREALSGRSDKRSLAIQTWQQAETTVINQCNQLLSPSADPSYVVTYISHSFPQHRQYLCTGALILMHGHAENINSGNLGRVLREFSPEEVTSNIYTMVDVLLHHMQIELQQGHSLQDLMLKACASLAFFVWTNELLPLDILLLALIDRDDDPHALRIVISLLDRQELQQRVKLFCMTRGFPEHWLYSGIFKRVELQKALGNHLAWKDRYPVFFDDIAARLLPVIPLIIYRLIENDAMDTAERVLAMYTHLLAYYPLRFTFVRDILAYFYGHLPGKLIVRILNVLDVSKIPFSESFPQQISSTNPVMCPPLDYFTTLLLGIVNNVIPPLHNNSKSGSMGDVLNNTLRTTQNKPAAVSQSGPANASEGQKAFYQIQDPGTYTQLVLETAVIEILSLPVSASQIVQSLVQIVVNIQPTLIQSSNALHGGSNSVGQGSVLPTSPSGGSTDSLGATRSTPSVSGINTSNFASRSGYTCQQLSCLLIQACGLLLAQLPSDFHSQLYLETTRIIKENWWLKDGTRSLGEIDSAVGYALLDPTWAAQDNTSTAIGNVVALLHSFFSNLPQEWLEGTNVIIKQLRPVTSVALLRIAFRIMGPLLPKLANAHALFNKTLSSLLSILVDVFGKNSQTTIAVDASDIADIIDFLHHVVHYEGQGGPVQASSKPRPDVLALIGRASESLRPDIQHLLSHLNPNVNSSVYAASHPKLVQNPT
Length1614
PositionTail
OrganismVigna radiata var. radiata (Mung bean) (Phaseolus aureus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Vigna.
Aromaticity0.07
Grand average of hydropathy-0.056
Instability index46.44
Isoelectric point6.61
Molecular weight180603.34
Publications
PubMed=25384727

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12129
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     287.92|      93|     102|    1179|    1280|       1
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 1179- 1280 (144.50/104.69)	PGKLIVRILN..VLDVSKIPFSESfpQQISSTNPVMC...PPLDYFTTLLLGIVNNV.IPPLHNNSKSGSMGDVLNNTlRTTqnkPaavSQSGPANASEGQKAFYQIQ
 1282- 1380 (143.42/81.34)	PGTYTQLVLEtaVIEILSLPVSAS..QIVQSLVQIVVniqPTLIQSSNALHGGSNSVgQGSVLPTSPSGGSTDSLGAT.RST...P...SVSGINTSNFASRSGYTCQ
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     337.36|     131|     181|     191|     371|       2
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  191-  336 (203.40/163.21)	PLTSVHAIGSPAQSTI..EPLSCAAMSPVKSSDIssAGQqsKLRG...GSSVRNNDISNSslRQLCC..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................kiiliglEFSLKPVTyAEIFNhMLNWLLNWDQ..RQQGINESDVIKSWRPDKSVIAWLHSC..LDVIWL.LVDEG....KCRVPFYELLRSDL
  376-  436 (52.17/69.31)	PTFGTHRILTQTTPTVsgEAVTHMRLSPITYSSV..LGE..PLHGediASSIQKGSLDWE..RAVRC...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
  990- 1073 (81.79/35.59)	...................................................................irhalrttpspdwwrrvlvlapcyrlssqmptagavfssemiceatidrivellkmtnseincwqdwlvfsdifyfliksgcidfvdfvdklvsrltegdhhilktnhvtwllaqiirieqvmnalntdprkvettrkilsfhredkssdpnnsqsilldfvsscqnlriwslnsstreylnneqlqkgkqidewwrqaskgdrmmdymnmdersigmfwvvtytmaqpacetvmnwlnsagvadllpgtnlqtaerlmatrevsplpmsllagfsinlcvklsyqmedslfsgqvipsiamvetytrllllaphslfrshfnhlvqrnpsllskpgvtllvleilnyrllplyryqgkskalmydvtkiisaikgkrgdhrvfrlaenlclnlifslrdfflvkregkgptdftetlnrvtvitlailiktrgiadaehllylqnmleqimatshhtwsektlhhfpsvlrealsgrsdkrslaiqtwqqaettvinqcnqllspsadpsyvvtyishsfpqhrqylctgalilmhghaeninsgnlgrvlrEFSPEEVT.SNIYT.MVDVLLHHMQieLQQGHSLQDLMLKACASLAFFVWTNELlpLDILLLaLIDRDddphALRIVISLLDRQEL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     239.80|      79|     325|     499|     585|       3
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  499-  585 (115.49/116.00)	CWQdwLVFSDIFYFLIKSGCIDFVDFVDKLvSRLTEGDHHIL.......KTNHVTWLlaQIIrIEQVMnALNTDPRKVETT.......RKILSfHREDKSS
  827-  919 (124.31/88.75)	CLN..LIFSLRDFFLVKREGKGPTDFTETL.NRVTVITLAILiktrgiaDAEHLLYL..QNM.LEQIM.ATSHHTWSEKTLhhfpsvlREALS.GRSDKRS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.64|      18|     102|      68|      87|       4
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   68-   87 (30.28/23.52)	LPPPNEqfILDFEQLQSQFP
  171-  188 (34.36/19.59)	LPPPST..IANSSNFQSSNP
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     202.37|      66|     783|     629|     703|       8
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  629-  702 (106.26/95.68)	DEWW.....RQASKGDRMMDYMNMDERsigmfWVVTyTMAQPACETVM............NWLNSAG..VADLLPGTNLQTAErlMATREVSP
 1415- 1499 (96.11/63.23)	ENWWlkdgtRSLGEIDSAVGYALLDPT.....WAAQ.DNTSTAIGNVVallhsffsnlpqEWLEGTNviIKQLRPVTSVALLR..IAFRIMGP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12129 with Med23 domain of Kingdom Viridiplantae
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