<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12125

Description mediator of RNA polymerase II transcription subunit 16 isoform X1
SequenceMYSIPTHNHVFFFFFSLHPSPSTATFGHLRLFFFSVMNQIAATKEPEEASEKTNEAVSYEEEEPMEQESVIPATVFCIRLRQPKSNLLYKMSVPEICRNFSAVSWCGKLNAIACASETCARIPSSTGNPPFWIPIHIVIPERPTECAVFNVIADSPRDSVQFIEWSPTCCPRALLIANFHGRVTIWTQPSHGPANRVLDTGCWLREHEWRQDIAVATKWLSGVSLYRWFSSKQSAPANSRSTFEEKFVSQQCQTSARWPNFLCVCSVFSSGTVQLHWSQWPSSNATPPKWFCTSKGPLGCGPSGIMAGDAIITESGAMHVAGVPIVNPSTIVVWEVMPGPGNGFQVIPRTSTNNGVPPPISSPNWIGFAPLAAYLFSWQDYLLSEEKQGKSQTNQNHGGSIPLHCSPVSNFSAYVSPEAAAQSAATTTWGSGVTAVAFDPTCGGSVIAVVIAEGQYMSPYDPDEGPSITGWRVQRWESSLQHVVLHPIFGNPTSSMGGQPPMQTVWQTKVDLSIPPTNDFKNHQASASGMNTDVQKVAEFGFDKSKRVYFDPFDLPSDVRTLARIVYSAHGGEIGIAFLRGGVHIFSGPNFTPIDNYQIGVGSAIAAPAFSSTSCCSASVWHDTSKDQTILKIIRVLPPAIPISQVKTNSSYWERAIAERFWWSLLVGVDWWDAVGCTQSAAEDGIVSLNSVIAVLDADFHSLPSAQHRQQYCPSLDRIKCRLLEGANAQEVRAMVLDMQARLLLNMLGNGIESALINPSALVPDPWQLSSETLSSIDPEAVAVEPALVPCVQAYVDSVLDLASHFITRLRRYASFCRTLASHAVTAGTGNNRNVVASPTQSSATPATSQGGQNGTTSSSGSTQMQAWVQGAIAKISSTTEGVSNPAPNPPISGPSSFMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLLFCFFFRRTQLSRYVGGVQRTTDTNTQKPQSNGSAPAKVEEPVKPGSTLVRSDDGQAGRVHQLVTAPKGGEEPSPGRSRIGTGNAGQGYTFEEVKVLFLVLMDLCRRTAGLQHPLPVSQVGSNNIQVRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELHPPAEEWHRRNMFGGSWSDSDDLDSTNEAPKLVNLDFSSLETCDVYDGADVLLPRKRRMSERDAAFGLNTSVGLGAYLGIMGSRRDVVTALWKTGLEGIWYKCIRCLRQTCAFASPASTNLPSQNDKDIWWISRWAHGCPMCGGTWVRVV
Length1252
PositionTail
OrganismVigna radiata var. radiata (Mung bean) (Phaseolus aureus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Vigna.
Aromaticity0.09
Grand average of hydropathy-0.152
Instability index45.35
Isoelectric point6.35
Molecular weight136384.81
Publications
PubMed=25384727

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12125
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.38|      14|      18|       3|      16|       1
---------------------------------------------------------------------------
    3-   16 (29.32/21.03)	SIPTHNHVFFFFFS
   22-   35 (27.06/18.79)	STATFGHLRLFFFS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.14|      17|      21|     243|     259|       3
---------------------------------------------------------------------------
  243-  259 (31.69/18.33)	F...EEKFVSQQCQTS.ARWP
  261-  281 (22.45/10.65)	FlcvCSVFSSGTVQLHwSQWP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     121.94|      36|     638|     511|     547|       4
---------------------------------------------------------------------------
  511-  547 (59.64/43.03)	DLSIPPTNDFKNHQAsASGMNTDVQKVAEFGFDKSKR
 1152- 1187 (62.30/40.43)	DVLLPRKRRMSERDA.AFGLNTSVGLGAYLGIMGSRR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     130.38|      41|     161|     301|     350|       6
---------------------------------------------------------------------------
  301-  350 (62.11/58.21)	GPSgiMAGDAIIT.ESGAMHVAGVPIV.NPSTivvweVMPG.PgnGFQVIPRT
  465-  508 (68.27/39.21)	GPS..ITGWRVQRwESSLQHVVLHPIFgNPTS.....SMGGqP..PMQTVWQT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.50|      10|      18|     757|     766|       7
---------------------------------------------------------------------------
  757-  766 (18.84/10.62)	INPSALVPDP
  777-  786 (17.66/ 9.43)	IDPEAVAVEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.23|      16|      21|     152|     172|       8
---------------------------------------------------------------------------
  152-  171 (25.28/25.03)	IAD.SPRdsVQFieWS.PTCCP
  176-  193 (22.95/ 6.24)	IANfHGR..VTI..WTqPSHGP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.43|      13|      22|     573|     591|      11
---------------------------------------------------------------------------
  573-  591 (15.04/23.97)	EIGIaflrgGVHIfSGPNF
  598-  610 (23.39/12.09)	QIGV.....GSAI.AAPAF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12125 with Med16 domain of Kingdom Viridiplantae
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