<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12124

Description mediator of RNA polymerase II transcription subunit 16 isoform X3
SequenceMGQLIVYSILAAGCESMSGDKTLQLLQSGSRECPWWFSSKQSAPANSRSTFEEKFVSQQCQTSARWPNFLCVCSVFSSGTVQLHWSQWPSSNATPPKWFCTSKGPLGCGPSGIMAGDAIITESGAMHVAGVPIVNPSTIVVWEVMPGPGNGFQVIPRTSTNNGVPPPISSPNWIGFAPLAAYLFSWQDYLLSEEKQGKSQTNQNHGGSIPLHCSPVSNFSAYVSPEAAAQSAATTTWGSGVTAVAFDPTCGGSVIAVVIAEGQYMSPYDPDEGPSITGWRVQRWESSLQHVVLHPIFGNPTSSMGGQPPMQTVWQTKVDLSIPPTNDFKNHQASASGMNTDVQKVAEFGFDKSKRVYFDPFDLPSDVRTLARIVYSAHGGEIGIAFLRGGVHIFSGPNFTPIDNYQIGVGSAIAAPAFSSTSCCSASVWHDTSKDQTILKIIRVLPPAIPISQVKTNSSYWERAIAERFWWSLLVGVDWWDAVGCTQSAAEDGIVSLNSVIAVLDADFHSLPSAQHRQQYCPSLDRIKCRLLEGANAQEVRAMVLDMQARLLLNMLGNGIESALINPSALVPDPWQLSSETLSSIDPEAVAVEPALVPCVQAYVDSVLDLASHFITRLRRYASFCRTLASHAVTAGTGNNRNVVASPTQSSATPATSQGGQNGTTSSSGSTQMQAWVQGAIAKISSTTEGVSNPAPNPPISGPSSFMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLLFCFFFRRTQLSRYVGGVQRTTDTNTQKPQSNGSAPAKVEEPVKPGSTLVRSDDGQAGRVHQLVTAPKGGEEPSPGRSRIGTGNAGQGYTFEEVKVLFLVLMDLCRRTAGLQHPLPVSQVGSNNIQVRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELHPPAEEWHRRNMFGGSWSDSDDLDSTNEAPKLVNLDFSSLETCDVYDGADVLLPRKRRMSERDAAFGLNTSVGLGAYLGIMGSRRDVVTALWKTGLEGIWYKCIRCLRQTCAFASPASTNLPSQNDKDIWWISRWAHGCPMCGGTWVRVV
Length1060
PositionTail
OrganismVigna radiata var. radiata (Mung bean) (Phaseolus aureus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Vigna.
Aromaticity0.08
Grand average of hydropathy-0.154
Instability index44.05
Isoelectric point6.30
Molecular weight114395.97
Publications
PubMed=25384727

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12124
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     928.48|     348|     562|      89|     485|       1
---------------------------------------------------------------------------
   89-  485 (553.19/378.85)	PSsnATPPKWFCTSKGPLGCG.PSGIMAGD..AIITESGA.....MHVAGV..PIVNPSTIVvwevmPGPgngFQVIPRTSTNNGvPPPIS.SPNWIgfaP.LAAYLFSWQD...YLLSEEKQGKS..QTNQNH......GGSIPLHCSPVSNfSAyvSPEAAAQSAATTTWGSGVTAvaFDPTCGGSVIAV.VIAEG.QYMSPYDPDEGPS....................................................................................................................................itgwrvqRWESSLQHvvlhPIfgnPTSSMGG...QPPMQ......TVWQTKVDLSIPP..TNDFKNHQASASGM...NTDVQKVAEfgfDKSKRVYF.......DPFDLPSDVRTLARIVYSA.HGGEI..GIAFLRGGVHIFSGPNFTPIDNYQIGVGSAIAapAFSSTSCCSASVWHdTSKDQTILKIIRVLPPAIPI.SQVKTN.SSYWERAIaerfWWsllvgVDWWdAVGC
  512-  704 (166.85/73.44)	PS..AQHRQQYCPSLDRIKCRlLEGANAQEvrAMVLDMQArlllnMLGNGIesALINPSALV.....PDP...WQLSSETLSSID.PEAVAvEPALV...PcVQAYVDSVLDlasHFITRLRRYASfcRTLASHavtagtGNNRNVVASPTQS.SA..TPATSQGGQNGTTSSSGSTQ..MQAWVQGAIAKIsSTTEGvSNPAPNPPISGPS................................................................................................................................................................................................................................................................................................................................................................................
  844- 1049 (208.43/96.08)	....................................................................................................................................................................................................................sfmpisintgtfpgtpavrligdchflhrlcqlllfcfffrrtqlsryvggvqrttdtntqkpqsngsapakveepvkpgstlvrsddgqagrvhqlvtapkggeepspgrsrigtgnagqgytfeevkvlflvlmdlcRRTAGLQH....PL...PVSQVGSnniQVRLHyidgnyTVLPEVVEASLGPhmQNMPRPRGADAAGLllrELELHPPAE...EWHRRNMFggswsdsDDLDSTNEAPKLVNLDFSSlETCDVydGADVLLPRKRRMSERDAAFGLNTSVGLGAYLG..IMGSRRDVVTALWK.TGLEGIWYKCIRCLRQTCAFaSPASTNlPSQNDKDI....WW.....ISRW.AHGC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.37|      13|      27|     783|     797|       3
---------------------------------------------------------------------------
  783-  797 (20.24/16.71)	PGSTlvRSDDGQAGR
  813-  825 (25.13/14.16)	PGRS..RIGTGNAGQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12124 with Med16 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GGVQRTTDTNTQKPQSNGSAPAKVEEPVKPGSTLVRSDDGQAGRVHQLVTAPKGGEEPSPGRSRIGTGNA
2) GTGNNRNVVASPTQSSATPATSQGGQNGTTSSSGSTQ
754
636
823
672










Molecular Recognition Features






MoRF SequenceStartStop




NANANA