<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12123

Description mediator of RNA polymerase II transcription subunit 33A isoform X1
SequenceMEDVAEMTKAAQQKGSDPLLWAVQMYSNLNSAGEALPSVELAHFLVSYICWDNNVPILWKFLEKALTLQIVPPMLLLALLSVRVIPCRHVQPAAYRLYLELLKRHAFELKSQINRPDYQKVMKSVDSVLHLSSIFGVSQSEPGNLVVEFLFSIVWQLLDASLDDEGLLEFTADKKSRWATLYHDMELDRLDDNNSDKKTEHHEQLQNANTLMAVEMIGQFLQDKISSRILYLARQNLPAHWLCFTQRLQLLATNSLALRKSRTLSPEALLQLSSDSCMVLSREYKTNSQQKFQTVMSFEYLSSSASLCHGASHSALWIPLDLVLEDSMDGYQVSATSAIETISGLIKTLRAINGTSWHDTFLGLWLATLRLVQRERDPIDGPMPHLDTRLCMLLCIIPLVVGDLIEEEEEEGIAVDEEENGPFDCWKGKKVPGKCRNDLVSSLQVLGDYQSLLAPPQSVVVAANQAAAKAILFVSGITVGSAYFDCLNMTEMPVDCSGNMRHLIVEACIARNLLDTSAYLWPGYVNGRINQIPQCMPAQVPGWSSFMKGAPLTSVMVNALVSSPATCLAELEKIFEIAIGGSEDEKISAAAILCGASLIRGWNIQEHTVHFILRLLSPPVPAENTEGNNYLINYAPILNVLFVGIASVDCVQIFSLHGLVPQLACSLMPICEVFGSCVPNISWTLTPGEEISAHAVFSNAFILLLKLWRFNRPPLEYGIGDVPTVGSQLTPEYLLLVRNSHLMSAGNVHKDRNRRRLSEIASLSSPNSVFVDSFPKLKVWYRQHQACIASTLSGLVHGTPFHQIVEGLLNMMFRKINRGSQTTITSGSSSSSGPANEDASIGPKLPAWDILEAIPFVVDAALTACAHGRLSPRELATGLKDLADFLPASLATIISYFSAEVTRGVWKPVYMNGTDWPSPAANLLNVEGQIRKILAATGVDVPSLASGDSSPATLPLPLAAFTSLTITYKVDKASERFLNLAGQTLESLAAGCPWPCMPIVASLWTLKAKRWTDFLIFSASRTVFLHNSDAVVQLLRSCFTATLGTNTSPLSSNGGVGALLGHGFKYHLCGGLCPVAPGILYLRAYRSIRDIVFLTEEIVSILMHSVREIVRSGLLRERLEKLKATKDGIRYGQASLAASMTRVKLAAALGASLVWISGGLMLVQLLIKETLPSWFISVQRFDQEEKCGGMVAMLGGYALAYFAVLCGAFAWGVDSSSSASKRRPKVLGTHMEFLASALDGKISLGCDSATWRAYVSGFVSLMVDCTPNWVLEVDVHVLKRLSNGLRQLNEEELALALLGVGGIGTMGAAAELIIDTGI
Length1318
PositionTail
OrganismVigna radiata var. radiata (Mung bean) (Phaseolus aureus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Vigna.
Aromaticity0.08
Grand average of hydropathy0.186
Instability index43.48
Isoelectric point5.94
Molecular weight144084.08
Publications
PubMed=25384727

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12123
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.31|      26|      42|     934|     964|       1
---------------------------------------------------------------------------
  934-  964 (34.15/31.17)	LAATGVDVPSLASGDSSPAtlpLPLAAftSL
  978- 1003 (50.16/28.38)	LNLAGQTLESLAAGCPWPC...MPIVA..SL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     169.73|      53|     278|     361|     415|       2
---------------------------------------------------------------------------
  361-  390 (39.75/20.83)	.............................................................................................................................................................................................................................................................FLGLWLATLRLVQRERDPID...GPMPHLDTRL
  391-  415 (15.73/12.43)	CML..lCiIPLVVGDLIEEEEEEGIAV...................................................................................................................................................................................................................................................................
  642-  667 (30.63/14.03)	...........................deeengpfdcwkgkkvpgkcrndlvsslqvlgdyqsllappqsvvvaanqaaakailfvsgitvgsayfdclnmtempvdcsgnmrhliveaciarnlldtsaylwpgyvngrinqipqcmpaqvpgwssfmkgapltsvmvnalvsspatclaelekifeiaiggsedekisaaailcgaslirgwniqehtvhfilrllsppvpaentegnnylinyapilnvlFVG..IASVDCVQIF..SLH...GLVPQLACSL
  671-  729 (83.62/54.11)	CEVfgsC.VPNISWTLTPGEEISAHAV..................................................................................................................................................................................................................................FSNAFILLLKLWRFNRPPLEygiGDVPTVGSQL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     138.95|      41|     126|     468|     509|       3
---------------------------------------------------------------------------
  423-  461 (22.89/ 8.33)	..................FDCWKGKKVPGKCRndlvsslqvlGDYQSLLAppqSVVV
  468-  509 (68.32/44.08)	AKAILFvSGITVG..SAYFDCLNMTEMPVDCS..........GNMRHLIV...EACI
  516-  548 (47.75/25.78)	TSAYLW.PGYVNGriNQIPQCMP.AQVP.GWS..........SFMK...........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     162.90|      52|     136|    1017|    1072|       5
---------------------------------------------------------------------------
 1017- 1072 (80.17/77.33)	FSASrTVFLHNSDAVVQL.....LRSCFTATlgTNTSPLSSNGGVGALLGhGF..KYH..LCGGL
 1149- 1209 (82.73/61.08)	LGAS.LVWISGGLMLVQLliketLPSWFISV..QRFDQEEKCGGMVAMLG.GYalAYFavLCGAF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.08|      26|      44|     822|     847|      12
---------------------------------------------------------------------------
  822-  847 (43.52/26.63)	TTITSGSSSSSGPANEDASIGPKLPA
  863-  888 (44.56/27.45)	TACAHGRLSPRELATGLKDLADFLPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     170.43|      54|     168|      76|     133|      13
---------------------------------------------------------------------------
   76-  133 (81.53/63.62)	LLALLSVRVIPCRHVQPAAyrlYLELLKRHAFELKSQINRPDYQKvMKSVDSVLHLSS
  250-  303 (88.90/56.63)	LLATNSLALRKSRTLSPEA...LLQLSSDSCMVLSREYKTNSQQK.FQTVMSFEYLSS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12123 with Med33 domain of Kingdom Viridiplantae
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