<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12110

Description probable mediator of RNA polymerase II transcription subunit 26b
SequenceMLRMNKGSLDYWRNYFGAANSDIFGIIDHAIMVAASDCPEEFRMRRDGIAERLFSSRLSRCLGCERVELSVPVDDDGGGCKNGFEGTGAEFESEAGASKESKVNSASVDDPGVTNTNRASNYSYGEAEALTDEIEEESQYVEEVFRIKDVLLNCEEESDSVLFDSLRRLQLMELTVDLLKATEIGKAVNPLRKHGSSDICLLARTLIEGWKEMVDDWVKATTAIAGSEGTPDSVNPSVIDDEEGLPSPPMDEGALFAPPTGSMELSQFFDGMDDDGNPRHSGEFMKNRDHGRSPSLKRKPQASNGANIVAKDGGKGQQAKKNEVAVRPNKPAISDSGPGRPPKSTMQKKGSIEPKVQQNTVKNTIPKNPHVRQLDKPRCSDDASVQVKLEASKRKLQERYQQVENAKRQRTVQVMELHDLPKQGIGHRNPHVKPGNQKRQWGHGRR
Length446
PositionUnknown
OrganismVigna radiata var. radiata (Mung bean) (Phaseolus aureus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Vigna.
Aromaticity0.05
Grand average of hydropathy-0.800
Instability index41.33
Isoelectric point5.85
Molecular weight49259.52
Publications
PubMed=25384727

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP12110
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     169.02|      45|      45|     334|     378|       1
---------------------------------------------------------------------------
  291-  332 (33.23/15.08)	.....GRSPslKRKpqasnganiVAKDGG...KGQQAK.KNEV...................AVRP.....NKPA
  334-  378 (81.62/46.71)	SDSGPGRPP..KST.........MQKKGSIEPKVQQNTVKNTI...................PKNPHVRQLDKPR
  380-  439 (54.16/28.76)	SDDASVQVK..LEA.........SKRK..LQERYQQ..VENAKrqrtvqvmelhdlpkqgigHRNPHVKPGNQKR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      86.78|      31|     162|      63|     110|       2
---------------------------------------------------------------------------
   73-   83 ( 9.95/10.60)	.......................VDDDGGGCKNG
   84-  103 (24.19/14.71)	FEGTGAEFESEAGASKESKV..............
  249-  282 (52.63/28.33)	PMDEGALFAPPTGSMELSQFfdgMDDDGNPRHSG
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP12110 with Med26 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) TTAIAGSEGTPDSVNPSVIDDEEGLPSPPMDEGALFAPPTGSMELSQFFDGMDDDGNPRHSGEFMKNRDHGRSPSLKRKPQASNGANIVAKDGGKGQQAKKNEVAVRPNKPAISDSGPGRPPKSTMQKKGSIEPKVQQNTVKNTIPKNPHVRQLDKPRCSDDASVQVKLEASKRKLQERYQQVENAKRQRTVQVMELHDLPKQGIGHRNPHVKPGNQKRQWGHGRR
221
446

Molecular Recognition Features

MoRF SequenceStartStop
1) NQKRQWGHGRR
2) QAKKNEVAVRPNKPAI
436
318
446
333