<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12082

Description mediator of RNA polymerase II transcription subunit 8
SequenceMQIIGERAPGMEGTGGGGAAGAGGEGEDRLNQAVQQQLNLKQVKTRAISLFKAISRILEDFEAYGRTNTTPKWQDILGQYSMVNLELFNIVDDMKKVSKAFVVHPKNVNAENASILPVMLSSKLLPEMEAEENSKREQLLEGMQNQNLPIPTQIEKLKARLDMIAAACEGAEKVLADTRKAYCFGTRQGPIAPTLDKGQAAKIQEQENLLRAAVNAGDGLRIPLDQRQITPAPPIHLADALPGLIDPPSHDASSAPNTMYIKNTPLSSNTMPPQNPLLQSSASQLLGRSAASPSAPTSTTSFDNTTPSPMPYANSPRSSTNIMNTPSPQQQTSQQQAPVQQQQQQQQQRQKLMQLPQQQQMLAQQQQLRQSAMQGLGQLHGQPQMQFSQPLGHQQFQGRQLPSGHVQHGIGQSQLNQGNQMTRLSQFSGPANSALFSAAQTTPNTQMIPNISGALPSQTLHPRMQFGLPGNNPQRSHTSQMLNDQMFNMGGGNPSGMMPIQQQQQQHGSQAFGSMASNAQNLQSGMVTLQNTQQNHPNFSQQRQQNPQ
Length548
PositionHead
OrganismVigna radiata var. radiata (Mung bean) (Phaseolus aureus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Vigna.
Aromaticity0.04
Grand average of hydropathy-0.701
Instability index54.45
Isoelectric point9.15
Molecular weight59650.39
Publications
PubMed=25384727

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12082
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.88|      17|      18|     456|     473|       3
---------------------------------------------------------------------------
  456-  473 (30.60/16.04)	PSQTLHPRMqFGLPGNNP
  478-  494 (30.28/11.59)	TSQMLNDQM.FNMGGGNP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      74.58|      16|      16|     378|     393|       4
---------------------------------------------------------------------------
  378-  393 (31.81/16.00)	QLHGQ..PQM....QFSQPLGH
  395-  412 (20.46/ 7.16)	QFQGRqlPSG....HVQHGIGQ
  414-  433 (22.31/ 8.61)	QLNQG..NQMtrlsQFSGPANS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.83|      17|      18|     292|     309|       5
---------------------------------------------------------------------------
  292-  309 (27.31/17.49)	SPSAPTSTTSFDNtTPSP
  312-  328 (29.52/14.39)	YANSPRSSTNIMN.TPSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     124.95|      39|     145|     103|     142|       8
---------------------------------------------------------------------------
  103-  142 (61.12/37.47)	VHPKNVNAENAS....ILPVMLSSKLLPEMEAEENSKREQLLeG
  245-  287 (63.83/35.27)	IDPPSHDASSAPntmyIKNTPLSSNTMPPQNPLLQSSASQLL.G
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12082 with Med8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LRIPLDQRQITPAPPIHLADALPGLIDPPSHDASSAPNTMYIKNTPLSSNTMPPQNPLLQSSASQLLGRSAASPSAPTSTTSFDNTTPSPMPYANSPRSSTNIMNTPSPQQQTSQQQAPVQQQQQQQQQRQKLMQLPQQQQMLAQQQQLRQSAMQGLGQLHGQPQMQFSQPLGHQQFQGRQLPSGHVQHGIGQSQLNQGNQMTRLSQFSGPANSALFSAAQTTPNTQMIPNISGALPSQTLHPRMQFGLPGNNPQRSHTSQMLNDQMFNMGGGNPSGMMPIQQQQQQHGSQAFGSMASNAQNLQSGMVTLQNTQQNHPNFSQQRQQNPQ
220
548










Molecular Recognition Features






MoRF SequenceStartStop




NANANA