<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12075

Description U-box domain-containing protein 33 isoform X1
SequenceMAVVSPVLATSQRMGSVRSPSHASGEILEEPNPGVVDQPIYVAVAKEVKESRSNLIWAIQHSGGKRICILYVHVRATMIPLLGGKFPTSALKEEQVQAYWEEEKQNMHRTLDEYLQICQRMGVRAEKLHIEMDSIEKGIIELVSQHGIRKLVMGAASDKYYNRRMMDLRSKKAIYVCKQAPAYCHIQFICKGHLIHTRDHSLNEGNVEVASPLVQQVPNSVRTFRSQSVTLGQGRRGNLTNDARRLRSASDGHVATFPAVSSPEETVGFSTPRDRMGTEVSSDESERLSMMSPSGLSISSESAVDLALTPGLITEGSENALELTMSQLVIEDLHHSSPPSTLQDGGIDDTIYDQLQQAMTEAEDASLTAYKETVRRRNAEKEAFEAIRKAKASESLYTEELNLRKLAEEELRKEKEELENAKRLRDKVREELHLALDQKASLESQIASSELIIKELEQKIVSAVDLLQSYKNEREELQIQRDNALREAEELRKKQGEASSSHVPQLFSEFSFSEIKEATDNFNPSLKIGEGGYGSIFKGVLSYTEVAIKRLHSDSMQGPLEFQQEVDVLSKLRHPNLITLIGACPDAWALVYEYLPNGSLEDRLACKDNTPPLSWQTRIRVATELCSALIFLHSSKPHSIVHGDLKPSNILLDANLISKLSDFGICRILSNCEGSSSNSTEFWKTDPKGTFVYMDPEFLASGELTPKSDVYSFGIILLRLLTGRPALGITKEVKYALDTGKLKSLLDPVAGDWPFVQAEQLARLALRCCDMNRKSRPDLYSDVWRILDAMRVSSGGTNSFGLSSEGLSQPPSYFICPIFQEVMRDPHVAADGFTYEAEAIRGWLDGGNDNSPMTNGKLAHHNLVPNRALRSAIHDWLQNH
Length880
PositionTail
OrganismVigna radiata var. radiata (Mung bean) (Phaseolus aureus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Vigna.
Aromaticity0.06
Grand average of hydropathy-0.394
Instability index51.99
Isoelectric point5.76
Molecular weight98117.07
Publications
PubMed=25384727

Function

Annotated function Functions as an E3 ubiquitin ligase.
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP12075
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     102.81|      33|      98|     315|     372|       1
---------------------------------------------------------------------------
  261-  293 (57.13/50.26)	SSPEETV...GF.STPRDRMGTEVSSDESERLSMMSP
  336-  372 (45.68/28.40)	SSPPSTLqdgGIdDTIYDQLQQAMTEAEDASLTAYKE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     356.02|     102|     280|     484|     588|       2
---------------------------------------------------------------------------
  484-  588 (161.29/83.16)	ALREAEELRKKQGEAsSSHVPQLFSEFSFSeiKEATDNF...NPSLKIGEGGY.GSIFKGVLSYTEVAIKRL..HSDSMQGPLEFQQEVDVL..SKLRHPNLI...TLIGACPDAW
  710-  753 (40.30/14.00)	............................................................VYSFGIILLRLL..TG...RPALGITKEVKY....ALDTGKLK...SLLDPVAGDW
  765-  876 (154.43/72.54)	ALRCCDMNRKSRPDL.YSDVWRILDAMRVS..SGGTNSFglsSEGLSQPPSYFiCPIFQEVMRDPHVAADGFtyEAEAIRGWLDGGNDNSPMtnGKLAHHNLVpnrALRSAIHD.W
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.14|      30|     104|       8|      38|       3
---------------------------------------------------------------------------
    8-   38 (48.46/33.91)	LATSQRMGsVRSPS.HASGEILEEPNPGVVDQ
  115-  145 (47.68/28.79)	LQICQRMG.VRAEKlHIEMDSIEKGIIELVSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.04|      16|      16|     399|     414|       5
---------------------------------------------------------------------------
  399-  414 (24.70/17.73)	EELNLRKLAEEELRKE
  416-  431 (25.35/18.41)	EELENAKRLRDKVREE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.18|      10|      19|     219|     228|       6
---------------------------------------------------------------------------
  219-  228 (17.95/10.80)	NSVRTFRSQS
  241-  250 (17.23/10.10)	NDARRLRSAS
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP12075 with Med32 domain of Kingdom Viridiplantae

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