<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12072

Description mediator of RNA polymerase II transcription subunit 33A isoform X1
SequenceMESALEWNDEVREGVLKRLKLWQQCSKKPAAALVTELVEHLNTLGIALPSPELGELLVSQICFDNNHPWMWKFTHHALSSRLLFPLQILSLLASNAIPHRHSHPHSFALFLPLLSQYAFSFQSTPSLSCNRKIVSSVDSALRISETYKVRDLEIGHVFVLFFYEIVISLLDCVLIDWGFQVTFSEKSSLVAAGKGEDCMDIDRNVTQNFEKSEYREQIRKRNSFTALEVLERLTESRKATILLQSVLLNMPEKFNCLQQRLQFLESLELASSELKLVNQVLTKVSANMRGVSHFDYSLSKHRLVGTLINMGSCKIPLKCNYRFCQSPCWVPFDIYMENAMDSRQIPTKSAIDVLTEGIKTLQMLNQASWQETFLALWLSALRLVQRERDPPEGPIPHLVARLCVLLCIVPLAIANVLRDASEHNLSSVQVSMESEYTHEMKSDDSVKRELMSSVQVLGHFSGLLCPPTLVIDAANQAARKAASFIYNSMNGKGESGTGIHANANTKAGGNLRHLIVEACIARNLMDTSVYFWPGYVSTSVLSLSDSSPPEKSPWSMFMEGTPLNNTLINSLTMTPASSLAEIEKLYYIALNGSDVERPAAAKILCGASLGHGWYIQEHVIHHVIKLLASPLPPSHAGSRSLLVDNMPMLCAVLRGASSVDTVHILSLHGVVPTVAAALLPLCEAFGSIKPTSNSTGDESSTTYMAFSLAFLFLIRLWKFCRPPLDLCITELGVAVGGLEYILSLHNHRVMYSQDKRKSNPNLPESASVKPVYIDSFPKLRALYCQYKSCVASALSGISTGNSIHQTANMILSMIYQKITKVGISSSNSSSPTSSNACSSLINSGEDAFQRPMLPGWEVLEALPFVLESILTACAHGRISSRELTTGLRDLVDFLPASLAAIIDYFSSEVTRGVWKLVPMNGTDWPSPAALLPSIELEINAILTHVGVEVPNCSSGGSPVMLPLPMAALVSLSITFKLDKSLEYMHAITGAALENCASGCPWPSMPIIGSLWAQKVRRWHNFIVVSGSRSVFRQNNESVAQLLRSCFTSFLGTLSVSTSKLTSECGVNGLLGSTITAPGAYPYVAPGFLFLRSCRNIHNVQYVNDIIVGLVTEYSNELAGRRSDAGSRHIKSNESSLSLAAQSAKEVATLGASLLCAAGGMLLVQELYKETIPTWLLSSRDMKKNNDSVASYILEGYAMAYLLILSGSIIWGVGTKLPPGTFSRRSRTIEVHLDFLAEVMEKKISLSCNPITWKTYVCCFVGFMVSLAPVWIQEVRVDTLKKLALGLSRWNEHEIALSLLHRGGLAAMGALAELVTVVESERMLPPS
Length1326
PositionTail
OrganismVigna radiata var. radiata (Mung bean) (Phaseolus aureus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Vigna.
Aromaticity0.08
Grand average of hydropathy0.132
Instability index45.91
Isoelectric point7.06
Molecular weight145688.94
Publications
PubMed=25384727

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12072
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.50|      21|      30|     850|     870|       1
---------------------------------------------------------------------------
  850-  870 (37.41/26.05)	RPMLPGW.EVLEALPFVLESIL
  881-  902 (29.09/18.38)	RELTTGLrDLVDFLPASLAAII
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.47|      19|      25|     796|     814|       2
---------------------------------------------------------------------------
  796-  814 (34.84/23.57)	GISTGNSIHQT.ANMILSMI
  822-  841 (29.63/18.79)	GISSSNSSSPTsSNACSSLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.28|      13|      26|      72|      86|       3
---------------------------------------------------------------------------
   72-   86 (19.18/14.82)	KFTH.HALSsrLLFPL
  100-  113 (19.10/ 7.91)	RHSHpHSFA..LFLPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.92|      16|      29|     740|     755|       5
---------------------------------------------------------------------------
  740-  755 (30.54/24.02)	YILSLHNHRVMYSQDK
  772-  787 (31.38/24.94)	YIDSFPKLRALYCQYK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.18|      12|      25|     419|     430|       6
---------------------------------------------------------------------------
  419-  430 (21.25/13.48)	DASEHNL.SSVQV
  444-  456 (15.93/ 8.17)	DSVKRELmSSVQV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.44|      15|      29|     917|     932|       9
---------------------------------------------------------------------------
  917-  932 (27.05/17.81)	VPmNGTDWPSPAAL.LP
  949-  964 (26.39/12.34)	VP.NCSSGGSPVMLpLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     166.85|      52|     930|     314|     378|      10
---------------------------------------------------------------------------
  314-  378 (78.11/94.32)	KIPLKCN.....YRFCqspCWVPFdiymenaMDSrqIPTKSAIDVLTEGIKTLQmLNQASWQETFLALWL
 1242- 1298 (88.74/64.53)	KISLSCNpitwkTYVC...CFVGF.......MVS..LAPVWIQEVRVDTLKKLA.LGLSRWNEHEIALSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     145.34|      46|     408|     637|     682|      12
---------------------------------------------------------------------------
  637-  682 (82.26/52.14)	GSRSLLVDNMPMLCAVLR.......GASSVDTVHILSLHGV.............VPTVAAALLPL..C
 1026- 1093 (63.08/38.21)	GSRSVFRQNNESVAQLLRscftsflGTLSVSTSKLTSECGVngllgstitapgaYPYVAPGFLFLrsC
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12072 with Med33 domain of Kingdom Viridiplantae
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