<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12060

Description mediator of RNA polymerase II transcription subunit 26-like isoform X1
SequenceMTAATATPQQMRDRLMQAIDGQNNQICNMVAVMDVISYLEKYPITKEALEETRLGKLINDVRKKTKDEDLVKRAKKLLRTWQKLIEPGQSEAQSKGHRGPPGAANGGNNPCRTDVSPPAAIPPSDKMVSELKSRNDFNNCYSPKAEKSGNRKRKGEQRDGQHLPAKISKKTANERTRNSQLPINGIGASPKAFMDTFDAHSHPKSDKDGADHLDNDRLNKIPINAVKPHPSSPGLAKPPSTSALLKTAVLQQQAKMDLVASGRGPHQPKSPHSNSYSPRRTKQDAVVKLSAPKATTLLSPAQSPRVMDSSGLGPSPLPSPQPLTSCIQGSLTVGPPSAESALHQDGPADVDQRLQHSTMRPDSLHNSKATSRSKVKAEGNGAATSTARKRRNKYRSRDYTVNLCGQPTEESTKPCRLKDRRLTFDPVTGQIKSWTHKESYPEWEAVVPVMPEPPRTELLKQNQYVQNPPVTPSPFQQTNWKELSRNEIIQSYLNRQSNVLTSSGAQTSGAHFFMNEYMEHHIKESRKTHVLVPNIPDMDLPEVSREVINEDLDRIHKEHWPGVNGCHDTKDNWYDWTECISLEPHGDESKLNILPYVCLD
Length600
PositionUnknown
OrganismSalmo salar (Atlantic salmon)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Protacanthopterygii> Salmoniformes> Salmonidae> Salmoninae> Salmo.
Aromaticity0.04
Grand average of hydropathy-0.901
Instability index54.37
Isoelectric point9.26
Molecular weight66671.33
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12060
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.15|      15|      48|     256|     272|       1
---------------------------------------------------------------------------
  256-  272 (27.36/19.13)	MDlvASGRGPHQPKSPH
  307-  321 (30.79/15.80)	MD..SSGLGPSPLPSPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.69|      34|      41|     101|     135|       2
---------------------------------------------------------------------------
  101-  135 (57.73/38.08)	PGAANGGNNPCRTDVSPPAAIPP..SDKMVSElKSRN
  143-  178 (53.96/31.10)	PKAEKSGNRKRKGEQRDGQHLPAkiSKKTANE.RTRN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12060 with Med26 domain of Kingdom Metazoa
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