<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12047

Description mediator of RNA polymerase II transcription subunit 23 isoform X3
SequenceMAISMETQLQSIFEDVVKTEVIEEAFAGMFMDTPEDERTKLISCLGAFRQYWSTLPPDSHDQCVQWIVRFIHGQHSPKRISFLYDCLAMAVETSLLPPRMVCQALISSDNLEWERTQLWALTFRLIRKIIGGVDYKGVRDLLKALLDKIQTIPNTVSSAVVQQLLAAREVVEYILDRNACLLPAYFAITEIRKLYPEGMLSHWLLGSLMSDFVDSFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPTTLRFPLRGMLPFDKDLFEPQTGLLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEEQFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDISKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLKLHHEFLQQSLRNKSLGMTDYKIALLCNAYSTNSECFTLPMGVLVETIYGNGSMRITLPGTNCTASGSVTPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSIALAPALVETYSRLLVYMEIESLGIKGFISQLLPNVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMNFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMTNENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGFRYTTKVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENAPEHWLQSDWHTKHMTYHKKYPEKLYFEGLAEQVNPPMQQQSHYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYERHLRDRTNLKRKLVHAIMSSLKDNRAPGWCLSETYIKCGMNPREDNVWIPDDTYYCKLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKDVGNALLSVVLKSQPLVPRENITAWMNAIGLVITALPEPYWVVLQDRIVSVLGSPCFTTETEWVGYPFALLDFTACHQSYSEMYCSYVLALAHAVWHHSSIGQLSLIPKFLSEVLKPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMLEIGVAFYEMLQAVDQHSQHLSYMDPICDFLYHIKYMFTGDSVKDQVEKIILTLRPAMKLRLRFITHTSKMEPAAASVPQPSSSVSSPAPQSNPGPSNLPLSVAQ
Length1380
PositionTail
OrganismSalmo salar (Atlantic salmon)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Protacanthopterygii> Salmoniformes> Salmonidae> Salmoninae> Salmo.
Aromaticity0.10
Grand average of hydropathy-0.028
Instability index45.05
Isoelectric point7.19
Molecular weight157599.21
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12047
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     154.48|      56|     789|      73|     218|       1
---------------------------------------------------------------------------
  118-  197 (75.48/180.68)	LWA.LTFRLI..................RKIIGGVDYKGVRDLLKALLdkiQTIPNTVssavvqqllaarevveyilDRNAclLPAYFAITEIRK.LYPE
  334-  409 (79.00/23.27)	LWQhLSSQLIffvlfqfasfphmvlslhQKLAGRGLIKGRDHLMWVLL...QFISGSI...................QKNA..LADFLPVMKLFDlLYPE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     113.18|      36|     789|      73|     110|       2
---------------------------------------------------------------------------
   73-  110 (62.58/45.28)	GQHSPKRISFLYD...............CLAMAVETSllPPRMVC....QALISSDN
  848-  902 (50.60/30.48)	GQQLNKCIEILNDmvwkynivtldrlilCLAMRSHEG..NEAQVCyfiiQLLLLKPN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      98.70|      20|     790|     199|     218|       3
---------------------------------------------------------------------------
  199-  218 (38.66/25.99)	MLSHWLLGSLMSDFVDSFRP
  995- 1009 (28.63/17.14)	LLDH..LGGLYK.FHD..RP
 1029- 1048 (31.41/19.59)	NLKRKLVHAIMSSLKDNRAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.24|      25|      30|     472|     496|       6
---------------------------------------------------------------------------
  472-  496 (45.78/30.18)	GMTDYKIALLCNAYSTNSECFTLPM
  505-  529 (45.46/29.91)	GNGSMRITLPGTNCTASGSVTPLPM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.68|      14|      18|    1050|    1064|       8
---------------------------------------------------------------------------
 1050- 1064 (26.19/18.03)	WCLSETYIkCGMNPR
 1069- 1082 (29.48/15.97)	WIPDDTYY.CKLIGR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.84|      18|      18|    1190|    1207|       9
---------------------------------------------------------------------------
 1190- 1207 (35.55/20.76)	E.WVGYPFALLDFTACHQS
 1210- 1228 (30.29/16.60)	EmYCSYVLALAHAVWHHSS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12047 with Med23 domain of Kingdom Metazoa
Unable to open file!