<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12034

Description mediator of RNA polymerase II transcription subunit 25-like isoform X4
SequenceMDLPIKPGANQVADVVFVIEGTANLGPYFESLRKHYILPAIEYFNGGPPAETDFGGDYGGTQYGLVVFNTVDCAPESYVQCHAPTSSAFEFVSWIDSIQFMGGGAESCSLIAEGLSVALQLFDDFKKMREQIGQTHKVCVLLCNSPPYLLPAVESVSYTGCTADNLVKIIRDRGIHFSVVSPRKLPALRALFDRASPVGGPVDPHPDYSQDPFHMILVRGISLPVSSGGGSGPLKPILPPQPLPVSQPPLGPASQAPPPISTAHPYQPPPSLNAAQAAAQMAVEAANNQKSRFPGMVNPGPPFSGQSTLPSVAGVKLAPSSQPSLSTVTTVSTPMLPQQQAPPPQQQQVQPPGQPQPNQQQPVPPQQQQPIANQQTPPSSQPGMPGVSAAQANPIGGQQQGVANKIVAWSGVLEWQEKPKASSMDSNTKLTRSLPCQVQVNQGENLNADQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFLFTNKDVESLKGLYRIMATGFAGCVHFPHSAPCEVRVLMLLYSSKKRIFMGLIPNDQSGFVNGIRQVITNHKQVQQHRSLGSGGPMPGPPGQVQPNQNFLNRPQGPIPVSHGNVQQQMTMRASGAPNQQLPVTGAPPNQVTQGGQAPPQGAMLRLPNPGANPQLRSLLLSQQQPQGGVGHMQGMMPHQGLGGQLVHPTPGAGPQMQAQWRQPLAGQMMMAAGQRGPGAQPPGMPQVSSVMEDEILMDLI
Length729
PositionUnknown
OrganismSalmo salar (Atlantic salmon)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Protacanthopterygii> Salmoniformes> Salmonidae> Salmoninae> Salmo.
Aromaticity0.05
Grand average of hydropathy-0.306
Instability index52.37
Isoelectric point8.64
Molecular weight77721.01
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12034
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     515.56|      82|      84|     223|     304|       1
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  223-  304 (151.45/37.82)	LPVSSGGGSGP.LKPILPPQPLPVSQPP.......................LG.PASQAPPPISTA....HPYQP..P..PSLNAAQA....AAQMAVEAA....................NNQ..KSRFPGMV...............NPG......PP....FS
  309-  396 (100.91/22.88)	LPSVAGVKLAPsSQPSLS.TVTTVSTPM.......................L..PQQQAPPP..QQ....QQVQP..PgqPQPNQQQP...vPPQQQQPIA....................NQQtpPSSQPGM.................PGvsaaqaNP....IG
  419-  555 (69.75/13.67)	PKASSMDSNTK.LTRSLPCQ.VQVNQGEnlnadqwpqklimqlipqqllttLG.PLFRNSRMVQFL....FTNKD..V..ESLKGLYR....I..MATGFAgcvhfphsapcevrvlmllySSK..KRIFMGLIpndqsgfvngirqviTNH......KQ....VQ
  556-  634 (95.79/21.36)	QHRSLGSG.GP.M.PGPPGQVQP.NQNF.......................LNrP..QGPIPVSHG....N.VQQ..Q..MTMRASGA...pNQQLPVTGA....................P........PNQV...............TQG...gqaPPqgamLR
  635-  714 (97.66/21.92)	LP..NPGANPQ.LRSLLLSQQQP..QGG.......................VG.HMQGMMPHQGLGgqlvHP.TPgaG..PQMQA.QWrqplAGQMMMAAG..........................QRGPGAQ...............PPG......MP......
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     131.27|      41|      55|      38|      82|       3
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   38-   82 (67.13/48.90)	LPAIEYFNGGppAET.DFGGDygGTQYGLVVFNTVDCAPESYVQCH
   95-  136 (64.14/34.29)	IDSIQFMGGG..AEScSLIAE..GLSVALQLFDDFKKMREQIGQTH
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12034 with Med25 domain of Kingdom Metazoa
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