<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12028

Description mediator of RNA polymerase II transcription subunit 28
SequenceMSSSMGSGMFPGQQSAGPHPVGGPGQPGLLSGAPGNRVQGPNTLVDDLEASFEACFASLVSQDYVNGTDQEEIRTGVDQCIQKFLDVARQTECFFLQKRLQLSVQKPDQVVKEDVSELRNELQRKELLVQKHLSKLHHWQQVLEDVSVQHRKPSDLPPPGPLAFLEQASAILPAAPLKQS
Length180
PositionHead
OrganismSalmo salar (Atlantic salmon)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Protacanthopterygii> Salmoniformes> Salmonidae> Salmoninae> Salmo.
Aromaticity0.05
Grand average of hydropathy-0.437
Instability index53.51
Isoelectric point5.50
Molecular weight19661.00
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12028
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.28|      11|      22|       7|      18|       2
---------------------------------------------------------------------------
    7-   18 (18.70/13.31)	SGMfPGQQSAGP
   31-   41 (22.58/11.12)	SGA.PGNRVQGP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.92|      15|      28|     101|     116|       3
---------------------------------------------------------------------------
  101-  116 (22.88/15.10)	QLSVQKP.......DQVVkEDVS
  126-  147 (20.04/ 8.89)	ELLVQKHlsklhhwQQVL.EDVS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12028 with Med28 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MSSSMGSGMFPGQQSAGPHPVGGPGQPGLLSGAPGNRVQGPNT
1
43










Molecular Recognition Features






MoRF SequenceStartStop




1) FLEQASAILPAAPLKQ
164
179