<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12011

Description mediator of RNA polymerase II transcription subunit 27
SequenceMADAMNVGVNLEAFSQAISAIQALRSSVTRVFDSLKDGMKNKETLEGREKVFITEFQDNLQSVNRDLNELERLSTLVGRPSESHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNKLQYHAGLASSLLNQQSLKRSANQMGASAKRRPKVQPSTLVLPPQYVDDVISRIGRMFPDMSIELFRPNGTSAVLLVTLGKVLKTIVVMRSLFIDRTIVRGFNENVYSEDGKLDIWSKSNYQVFQKVTDHATTALLHYQLPQMPDVVVRSFMTWLRSYIKLFQTPCQRCGKFLQEGLPPTWRDFRTLEAFHDTCRQ
Length311
PositionTail
OrganismSalmo salar (Atlantic salmon)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Protacanthopterygii> Salmoniformes> Salmonidae> Salmoninae> Salmo.
Aromaticity0.08
Grand average of hydropathy-0.318
Instability index45.10
Isoelectric point9.38
Molecular weight35398.24
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12011
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     126.90|      29|      60|      70|      98|       1
---------------------------------------------------------------------------
   70-   98 (47.58/29.93)	LERLSTLVGRPSESHPLH.NSGLL.SLDPVQ
  101-  131 (36.49/21.40)	TPLYSQLLQAYKWSNKLQyHAGLAsSLLNQQ
  133-  160 (42.83/26.28)	LKRSANQMGASAKRRPKV.QPSTL.VL.PPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     122.46|      40|      59|     163|     203|       2
---------------------------------------------------------------------------
  163-  203 (61.66/41.29)	DDVISRIGRM..FPDMSIELFR...PNGTSAVLLVTLGKvLKTIVV
  219-  263 (60.80/36.56)	ENVYSEDGKLdiWSKSNYQVFQkvtDHATTALLHYQLPQ.MPDVVV
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12011 with Med27 domain of Kingdom Metazoa
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