<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12006

Description mediator of RNA polymerase II transcription subunit 24 isoform X4
SequenceMKVVNLKQAILQAWKERWSDYQWAINIKKNFPKGATWDYLNLAEALMEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLLAISKFDDFSRELCVKSLLEIMDMFCHRLSCHGKAEECIGLCRALLGVVVWLLTGCAWYCERLRELGPSASTEANLRACLERLRDLVNSQKNRALVHIARLEDQASWTNVEQALLKVTEGLNSLTNQTLRGKLEECISLVKSIPTILSEQSDPPHHSLFPSVHAFIMLEGTMNLTGETQPLVEQLMMIKRMQRIPAPVFVLEIWKACFTGLIESPEGTEELKWTAFTFLKIPQVLLRLKKYPQGEKDFMDDVNIAFEYLLKLTPLLDKADQRCNCDCLSMLLQECNKLSLLSDSNTTNLTSKREYAPRLKTAENANIQPNPGLILRAEPTVTNILKTVDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIKLNEFPKHISGEGSKSASVRALLFDISFLMLCHVVQTYGSEVILSDPSPSGETPFFETWLQTCMPEEGKTLNPDHPCFRPESGKVESLVALLNNSSEMKLVQMKWHEICLSTPAAILEVLNAWENGVLSVEAVQKITDNIKGKVCSMAICAVAWLVAHVRMLGLDEREKPQTMIRQLMTPLYGENTLQFYNERVVIMSSILENMCADVFQQTGLALRPPMEGQEPIPYRNLLSAKEPIHEALRKQFRSVLWKGWVDSGALHLFESLLHTGGVFWFTNNLVKELLKETRQEWANRVVELLYSIFCLDTQQITLTLLGHILPNLLTDSAHWHSLADPPGKALAKLSVWCALSSFSTHHKGQASARQRKRQREDIEDYSSLFPLDDTQPSKLMRLLSSNEDEPVVLSSPGDRSMSTSLSASQLHTVNMRDPLNRVLANLFLLISSILGSKTAGPHTQFVQSFMEECVECLEQGSRGSILQFMPFTMVSELVKLPALAKPKVVLGITDLTLPLGRRVAAKAISAL
Length983
PositionTail
OrganismSalmo salar (Atlantic salmon)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Protacanthopterygii> Salmoniformes> Salmonidae> Salmoninae> Salmo.
Aromaticity0.07
Grand average of hydropathy-0.040
Instability index45.00
Isoelectric point6.66
Molecular weight110044.74
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12006
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.27|      23|     115|     658|     681|       1
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  658-  681 (37.87/28.85)	IMSSILENMCADVFQQTGLAlRPP
  776-  798 (43.40/28.52)	LLGHILPNLLTDSAHWHSLA.DPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.78|      26|     113|     415|     440|       2
---------------------------------------------------------------------------
  415-  440 (45.60/27.71)	KTVDADHSK.SPE.GLLGVLGHMLSGKS
  531-  558 (38.18/22.05)	KTLNPDHPCfRPEsGKVESLVALLNNSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     119.86|      38|     182|     694|     748|       3
---------------------------------------------------------------------------
   27-   65 (63.06/30.26)	IKKNFpKGATW....D..YLNLAEALMEQAMIGPSPNPLILSYLK
  704-  747 (56.80/43.39)	LRKQF.RSVLWkgwvDsgALHLFESLLHTGGVFWFTNNLVKELLK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.01|      10|      17|     117|     126|       6
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  117-  126 (20.12/10.29)	CIGLCRAL..LG
  135-  146 (17.89/ 8.41)	CAWYCERLreLG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     220.64|      71|     677|     208|     282|       7
---------------------------------------------------------------------------
  208-  282 (111.90/87.43)	LRGKLEECI.SLVKSIPTILSEQSDPPHHSlFpsVHAFiMLEGTMNLTGETQPLVEQLM...MIKRMQRIPA...PVFVLEI
  887-  964 (108.74/70.15)	MRDPLNRVLaNLFLLISSILGSKTAGPHTQ.F..VQSF.MEECVECLEQGSRGSILQFMpftMVSELVKLPAlakPKVVLGI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.79|      21|      28|     294|     314|      10
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  294-  314 (37.82/23.59)	PEGTEELK...WTAFTF.LKIPQVL
  321-  345 (27.97/15.64)	PQGEKDFMddvNIAFEYlLKLTPLL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12006 with Med24 domain of Kingdom Metazoa
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