<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12003

Description mediator of RNA polymerase II transcription subunit 24 isoform X2
SequenceMKVVNLKQAILQAWKERWSDYQWAINIKKNFPKGATWDYLNLAEALMEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLLAISKFDDFSRELCVKSLLEIMDMFCHRLSCHGKAEECIGLCRALLGVVVWLLTGCAWYCERLRELGPSASTEANLRACLERLRDLVNSQKNRALVHIARLEDQASWTNVEQALLKVTEGLNSLTNQTLRGKLEECISLVKSIPTILSEQSDPPHHSLFPSVHAFIMLEGTMNLTGETQPLVEQLMMIKRMQRIPAPVFVLEIWKACFTGLIESPEGTEELKWTAFTFLKIPQVLLRLKKYPQGEKVQDFMDDVNIAFEYLLKLTPLLDKADQRCNCDCLSMLLQECNKLSLLSDSNTTNLTSKREYAPRLKTAENANIQPNPGLILRAEPTVTNILKTVDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIKLNEFPKHISGEGSKSASVRALLFDISFLMLCHVVQTYGSEVILSDPSPSGETPFFETWLQTCMPEEGKTLNPDHPCFRPESGKVESLVALLNNSSEMKLVQMKWHEICLSTPAAILEVLNAWENGVLSVEAVQKITDNIKGKVCSMAICAVAWLVAHVRMLGLDEREKPQTMIRQLMTPLYGENTLQFYNERVVIMSSILENMCADVFQQTGLALRPPMEGQEPIPYRNLLSAKEPIHEALRKQFRSVLWKGWVDSGALHLFESLLHTGGVFWFTNNLVKELLKETRQEWANRVVELLYSIFCLDTQQITLTLLGHILPNLLTDSAHWHSLADPPGKALAKLSVWCALSSFSTHHKGQASARQRKRQREDIEDYSSLFPLDDTQPSKLMRLLSSNEDEPVVLSSPGDRSMSTSLSASQLHTVNMRDPLNRVLANLFLLISSILGSKTAGPHTQFVQSFMEECVECLEQGSRGSILQFMPFTMVSELVKLPALAKPKVVLGITDLTLPLGRRVAAKAISAL
Length985
PositionTail
OrganismSalmo salar (Atlantic salmon)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Protacanthopterygii> Salmoniformes> Salmonidae> Salmoninae> Salmo.
Aromaticity0.07
Grand average of hydropathy-0.040
Instability index45.04
Isoelectric point6.66
Molecular weight110272.00
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12003
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.27|      23|     115|     660|     683|       1
---------------------------------------------------------------------------
  660-  683 (37.87/20.25)	IMSSILENMCADVFQQTGLAlRPP
  778-  800 (43.40/20.02)	LLGHILPNLLTDSAHWHSLA.DPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.78|      26|     114|     417|     442|       2
---------------------------------------------------------------------------
  417-  442 (45.60/31.09)	KTVDADHSK.SPE.GLLGVLGHMLSGKS
  533-  560 (38.18/24.71)	KTLNPDHPCfRPEsGKVESLVALLNNSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.85|      27|      31|     154|     182|       3
---------------------------------------------------------------------------
  154-  182 (39.40/27.81)	NLRACLERLRDLVNSQKNRALVhiARLED
  188-  214 (39.45/21.45)	NVEQALLKVTEGLNSLTNQTLR..GKLEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     180.04|      57|     677|     222|     282|       6
---------------------------------------------------------------------------
  222-  282 (89.93/82.23)	IPTILSEQSDPPHHSlFpsVHAFiMLEGTMNLTGETQPLVEQLM...MIKRMQRIPA...PVFVLEI
  904-  966 (90.11/65.23)	ISSILGSKTAGPHTQ.F..VQSF.MEECVECLEQGSRGSILQFMpftMVSELVKLPAlakPKVVLGI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     187.06|      59|     246|      82|     143|       7
---------------------------------------------------------------------------
   82-  143 (100.95/82.58)	ISKF.DD....FSRELCVKSLLEIMDMFCHrLSCHGK.AEECIGLcrALLG.VVVWLLTGCAWYCERLR
  326-  391 (86.11/58.49)	VQDFmDDvniaFEYLLKLTPLLDKADQRCN.CDCLSMlLQECNKL..SLLSdSNTTNLTSKREYAPRLK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     119.86|      38|     698|      27|      65|       9
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   27-   65 (63.06/36.46)	IKKNFpKGATW....D..YLNLAEALMEQAMIGPSPNPLILSYLK
  706-  749 (56.80/28.40)	LRKQF.RSVLWkgwvDsgALHLFESLLHTGGVFWFTNNLVKELLK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12003 with Med24 domain of Kingdom Metazoa
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