<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11996

Description cyclin-dependent kinase 19 isoform X2
SequenceMDYDFKTKLAAEREKVEDLFEYEGCKVGRGTYGHVYKAKRKDGEDEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGSERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFLEDPLPTSETRSNSTSRRQPRPSSRVAPSRLLTSRAPPRPTAMQGALEPTPGEASSTARIRGPPTRNLAPGLQEPPQALGSTSTPAPALVTKATSKVPLSPRDTRRHPSRAHSTHTSHTATEALRTGQGPLPNQPSTKNKP
Length476
PositionKinase
OrganismSalmo salar (Atlantic salmon)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Protacanthopterygii> Salmoniformes> Salmonidae> Salmoninae> Salmo.
Aromaticity0.08
Grand average of hydropathy-0.601
Instability index49.76
Isoelectric point9.58
Molecular weight53988.33
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11996
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      71.85|      15|      15|     343|     357|       1
---------------------------------------------------------------------------
  343-  357 (27.73/12.40)	SETRSNS..TSR.RQPRP
  359-  375 (22.79/ 9.04)	SRVAPSRllTSR.APPRP
  385-  399 (21.33/ 8.06)	TPGEASS..TARiRGP.P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.55|      28|      30|     416|     443|       3
---------------------------------------------------------------------------
  416-  443 (48.27/25.08)	STSTPAPALVTKATSKVPLSPR.DTRRHP
  448-  476 (44.29/22.47)	STHTSHTATEALRTGQGPLPNQpSTKNKP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11996 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SEQALQDPYFLEDPLPTSETRSNSTSRRQPRPSSRVAPSRLLTSRAPPRPTAMQGALEPTPGEASSTARIRGPPTRNLAPGLQEPPQALGSTSTPAPALVTKATSKVPLSPRDTRRHPSRAHSTHTSHTATEALRTGQGPLPNQPSTKNKP
326
476










Molecular Recognition Features






MoRF SequenceStartStop




NANANA