<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11990

Description mediator of RNA polymerase II transcription subunit 26-like isoform X2
SequenceMTTASATPQQMRDRLLQAIDSHSNIHNMVAVLEVITYLEKFPITKEALEETRLGKLINDVRKKTKDKDLAKRAKKLLRSWQKLIDPGQNETPSRGAVSVSGSANGSAHPCRTDVPPPDVSLAGKGVQEVKTRNDVHNTYSPKAEKSSSRKRRGEQKDSVHLPAKTSKMSPNEQMHNSTPPPPTNGIAGNPEAPQDLEATPSPDRARTEHIENEKHSRIPVNAVKPHPSSPGIAKLPSTSSLLKTAVLQQQARLDEGGGQYLTKSPRCASSPRTMKQETMSKHSSTYAPKGTIPSPARSPRLPSSQPLTSPAQVSHVNGPPPPAHRASLHWPGSTEATTNPPHSTATLEPLPVFLPTTHPAPQNSESAELHRPTPSSSVMVVKAEAEVSASSSDRKKRKKYRSRDYSVNLQGQDTEDKTKPVRLKERRLTFDPVTGQIKSMVHKEPCQVEEPPMPPSPKPQQRTDLHPQQPPTPSPFQQTNWKELSRNEIIQSYLNLQSNVLTSSRVQAPGAHFFMSEYLKREESDLREARRGVHVLQLDSSVTDTPGVSREVTDKDLHRVHTEHWQGVNGCYDTKGTWYDWTECISLDPHGDESKLNILPYICLD
Length605
PositionUnknown
OrganismSalmo salar (Atlantic salmon)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Protacanthopterygii> Salmoniformes> Salmonidae> Salmoninae> Salmo.
Aromaticity0.04
Grand average of hydropathy-0.906
Instability index65.30
Isoelectric point9.30
Molecular weight66977.42
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11990
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     296.73|      44|      44|     179|     222|       1
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  115-  163 (48.27/22.31)	.PPPDVSLAGKGvqevKTRNDVH....NTYSP.....kaEKSSSRKRRGEQKDSVHL..PA
  179-  222 (76.39/40.30)	PPPPTNGIAGNP....EAPQDLE....ATPSP.......DRARTEHIENEKHSRIPV..NA
  225-  268 (56.00/27.26)	PHPSSPGIAKLP....STSSLLK....TAVLQ.......QQARLDEGGGQYLTKSPR..CA
  319-  356 (51.05/24.09)	PPPPAHR..ASL....HWPGSTE....ATTNP.......PHS.TATLEP.....LPVflPT
  372-  406 (35.75/14.30)	PTPSSSVMVVKA....EA..EVS....AS.SS.......DRKKRKKYRSRDYS........
  451-  491 (29.28/10.17)	PPMPP...SPKP....QQRTDLHpqqpPTPSPfqqtnwkELSRNEIIQ.............
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11990 with Med26 domain of Kingdom Metazoa
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