<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11975

Description MTSS1-like protein isoform X1
SequenceMDSGIEKECSALGGLFQIIMNDMKASYPAWEDFVTKGVKLQSQLRATIVVTGSFLDAFQKVADMATGTRGATKEIGSALTRMCMRHRSIESKLKLFTTALTDTLINPLELKIEEWKKVASQLDKDHAKEYKKARADIKKKSSDTIKLQKKVKKGKDEVRGQLDSALQDVNVRYAVLEETEKRAACRALIEERGRYCSFVSMLKPVLDHEISMLGEVTHLQTILEDLSTLTAEPSKLPPASEQVILDLKGSDYSYSYQTPPASPSNTLSRKSSISGNYNSVRHVPSLDSITSSLDGVHLRPPSMESAQEVCGSWSGHTGSGTENGTAMPPPHNSYTQHGERARAMSTSGKPQSAREQLALALGGGLNSEAPRTSHDSLHCSSGYSTQTTTPSCSEDTIPSHAVKKELPLYDYDYICLHRGEEEHHGPPDFDKSSTIPRNSDLSLQYRKMFQSKRPASTVSLLAEPELLGLCQSHTATIRRKPSSKPAYRRGTISGGVPIPICTPQVPLKALGVEGGGGNCGRGGNSGSNENMGPPEGGMGMSWTVDHGLVHTKHSLCTSTQSLSAMPLHRSLSTSPYYSLIPGQAPVPMGSSEQLYQLSKQQQYALHQQQQKQYQQQHLQYNQQQQYQQQPQTHQVQPTAQTQQQQQTFQLQQRFQQQQLQQQQQLYQQQLQQQQQQKLQHQKQLQQQQLIQQQQQPIQQQSHLQQQHNTSGTANQLVESGHCLPPQQPPAAQEQDAKEPSGAGGHMVTMIRGVKLRRTLTNDRSAPFIPPPSHFK
Length775
PositionTail
OrganismSalmo salar (Atlantic salmon)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Protacanthopterygii> Salmoniformes> Salmonidae> Salmoninae> Salmo.
Aromaticity0.05
Grand average of hydropathy-0.762
Instability index61.87
Isoelectric point8.85
Molecular weight85846.47
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
actin binding	GO:0003779	IEA:InterPro

GO - Biological Process
plasma membrane organization	GO:0007009	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11975
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     103.90|      16|      16|     655|     670|       1
---------------------------------------------------------------------------
  611-  630 (24.24/ 7.25)	KQYQQQhLqynQQQQYQQQP
  646-  663 (25.35/ 7.90)	QTFQLQ..qrfQQQQLQQQQ
  664-  682 (26.51/ 8.59)	QLYQQQ.LqqqQQQKLQHQK
  683-  701 (27.80/ 9.35)	QLQQQQ.LiqqQQQPIQQQS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     117.69|      28|      40|     420|     447|       2
---------------------------------------------------------------------------
  378-  419 (25.04/12.75)	....HCSSGYSTQTTTPSCSedtipshavkkelplydyDYICLHRG
  420-  447 (49.66/34.19)	EEEHHGPPDFDKSSTIPRNS..................DLSLQYRK
  463-  489 (42.99/28.38)	EPELLGLCQ.SHTATIRRKP..................SSKPAYRR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      83.06|      16|      42|     318|     333|       3
---------------------------------------------------------------------------
  318-  333 (30.67/14.96)	GSGTENGTAMPPPHNS
  336-  350 (25.64/11.44)	QHG.ERARAMSTSGKP
  362-  376 (26.75/12.22)	GGGL.NSEAPRTSHDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.99|      18|      19|     222|     240|       4
---------------------------------------------------------------------------
  222-  240 (27.50/19.74)	ILeDLSTLTAEPS.KLPPAS
  244-  262 (29.49/16.44)	IL.DLKGSDYSYSyQTPPAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      67.87|      16|      18|     281|     297|       5
---------------------------------------------------------------------------
  263-  277 (16.01/ 6.16)	...PSNTlS...RKSSISGNY
  281-  297 (24.83/19.70)	RHvPSLD.S...ITSSLDGVH
  299-  316 (27.03/16.38)	RP.PSME.SaqeVCGSWSG.H
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.05|      11|      15|     552|     562|       6
---------------------------------------------------------------------------
  552-  562 (20.71/12.52)	KHSLCTST.QSL
  568-  579 (16.34/ 8.14)	HRSLSTSPyYSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.64|      11|      18|     128|     138|       9
---------------------------------------------------------------------------
  128-  138 (17.42/12.15)	KEYKKARADIK
  149-  159 (17.22/11.94)	KKVKKGKDEVR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11975 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GVEGGGGNCGRGGNSGSNENMGPPEGGMGMSWTV
2) QPIQQQSHLQQQHNTSGTANQLVESGHCLPPQQPPAAQEQDAKEPSGAGGHMVTMIRGVKLRRTLTNDRSAPFIPPPSHFK
3) SITSSLDGVHLRPPSMESAQEVCGSWSGHTGSGTENGTAMPPPHNSYTQHGERARAMSTSGKPQSAREQLALALGGGLNSEAPRTSHDSLHCSSGYSTQTTTPSCSEDTIPS
511
695
288
544
775
399










Molecular Recognition Features






MoRF SequenceStartStop




1) HMVTM
745
749