<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11974

Description MTSS1-like protein isoform X2
SequenceMDSGIEKECSALGGLFQIIMNDMKASYPAWEDFVTKGVKLQSQLRATIVVTGSFLDAFQKVADMATGTRGATKEIGSALTRMCMRHRSIESKLKLFTTALTDTLINPLELKIEEWKKVASQLDKDHAKEYKKARADIKKKSSDTIKLQKKVKKGKDEVRGQLDSALQDVNVRYAVLEETEKRAACRALIEERGRYCSFVSMLKPVLDHEISMLGEVTHLQTILEDLSTLTAEPSKLPPASEQVILDLKGSDYSYSYQTPPASPSNTLSRKSSISGNYNSVRHVPSLDSITSSLDGVHLRPPSMESAQEVCGSWSGHTGSGTENGTAMPPPHNSYTQHGERARAMSTSGKPQSAREQLALALGGGLNSEAPRTSHDSLHCSSGYSTQTTTPSCSEDTIPSHDYDYICLHRGEEEHHGPPDFDKSSTIPRNSDLSLQYRKMFQSKRPASTVSLLAEPELLGLCQSHTATIRRKPSSKPAYRRGTISGGVPIPICTPQVPLKALGVEGGGGNCGRGGNSGSNENMGPPEGGMGMSWTVDHGLVHTKHSLCTSTQSLSAMPLHRSLSTSPYYSLIPGQAPVPMGSSEQLYQLSKQQQYALHQQQQKQYQQQHLQYNQQQQYQQQPQTHQVQPTAQTQQQQQTFQLQQRFQQQQLQQQQQLYQQQLQQQQQQKLQHQKQLQQQQLIQQQQQPIQQQSHLQQQHNTSGTANQLVESGHCLPPQQPPAAQEQDAKEPSGAGGHMVTMIRGVKLRRTLTNDRSAPFIPPPSHFK
Length766
PositionTail
OrganismSalmo salar (Atlantic salmon)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Protacanthopterygii> Salmoniformes> Salmonidae> Salmoninae> Salmo.
Aromaticity0.05
Grand average of hydropathy-0.770
Instability index61.96
Isoelectric point8.81
Molecular weight84804.20
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
actin binding	GO:0003779	IEA:InterPro

GO - Biological Process
plasma membrane organization	GO:0007009	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11974
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      79.66|      16|      16|     646|     661|       1
---------------------------------------------------------------------------
  637-  654 (25.35/ 6.44)	QTFQLQ.qrfQQQQLQQQQ
  655-  673 (26.51/ 7.02)	QLYQQQLqqqQQQKLQHQK
  674-  692 (27.80/ 7.65)	QLQQQQLiqqQQQPIQQQS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.61|      18|      19|     222|     240|       3
---------------------------------------------------------------------------
  222-  240 (26.87/19.63)	ILeDLSTLTAEPS.KLPPAS
  244-  262 (27.75/15.37)	IL.DLKGSDYSYSyQTPPAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.93|      14|      15|     272|     286|       4
---------------------------------------------------------------------------
  272-  286 (21.79/18.06)	SISGNYNSV..RHvPSL
  288-  303 (21.13/12.02)	SITSSLDGVhlRP.PSM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.31|      17|      19|     341|     357|       5
---------------------------------------------------------------------------
  326-  342 (30.39/13.91)	AMPPPHNSYTQHGERAR
  343-  359 (25.91/10.87)	AMSTSGKPQSAREQLAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.33|      15|      19|     366|     383|       6
---------------------------------------------------------------------------
  364-  378 (26.23/10.19)	GLNSEA..PRTSHDSLH
  382-  398 (22.11/16.70)	GYSTQTttPSCSEDTIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.64|      11|      18|     128|     138|      11
---------------------------------------------------------------------------
  128-  138 (17.42/14.73)	KEYKKARADIK
  149-  159 (17.22/14.47)	KKVKKGKDEVR
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11974 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DYICLHRGEEEHHGPPDFDKSSTIPRNSDLSLQYRKM
2) GVEGGGGNCGRGGNSGSNENMGPPEGGMGMSWTV
3) QPIQQQSHLQQQHNTSGTANQLVESGHCLPPQQPPAAQEQDAKEPSGAGGHMVTMIRGVKLRRTLTNDRSAPFIPPPSHFK
4) SITSSLDGVHLRPPSMESAQEVCGSWSGHTGSGTENGTAMPPPHNSYTQHGERARAMSTSGKPQSAREQLALALGGGLNSEAPRTSHDSLHCSSGYSTQTTTPSCSE
403
502
686
288
439
535
766
394










Molecular Recognition Features






MoRF SequenceStartStop




1) HMVTM
736
740