<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11953

Description mediator of RNA polymerase II transcription subunit 26
SequenceMPNTAQELKEKFLRTLDNDNNVVDMVGVLETISALEKFPITREALEQTRLGRYVNEMRRKTTNKELARRAKDLVRSWQQLVAPQTTNTINGDNVALRSGGYQGQRLSPRITISPALSQTSRVSTPRGHASPALGPGAVASPALSTGKGNKYKAQGSPAKLAGSRSSPAGLSQSSSPGMPPTRSRPITPVSGGSSRSGTPINVQQATKISPGLPRASRPATPGSAQASRLSPGVVQPGGRQGAGKLVSPAVMERTKTSNGFECHSISPPTVSSVGVSETVDRTNIANRKRQRNGDTLPEQPSKKTPALVGSDSKDSKENACSTTVNGLLSIKCDRSGGAVQSPAIKSLSRSSSASSLNTQAAIALESKISPSGSSSKGGLSNRRNTNLSLKTEMDKSMVTSRTPKVKTTAQLIAELQAKSSSPNLGSKTIKKIQTNQIQKEVEVQESIVPAGAKPRPRRNPSVGTPTQLPRVGEVTLSQTKTELVQKFLQSSVTPEDLSSPLDSIGRTQSPANFDVSFANSDSLPNSADVSLQSVKSELDIYKEVINTEETYPKEELDPYSLLPPLNLDEIKLEEESNGDEVQSLPEVTDLTVERLNEERWPGINGNYDCDGEWNDWSKTISMPTYESETLHILPYVNIDD
Length640
PositionUnknown
OrganismLingula unguis
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Brachiopoda> Linguliformea> Lingulata> Lingulida> Linguloidea> Lingulidae> Lingula.
Aromaticity0.03
Grand average of hydropathy-0.643
Instability index63.37
Isoelectric point9.32
Molecular weight68554.86
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11953
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     170.26|      24|      24|     113|     136|       1
---------------------------------------------------------------------------
  100-  126 (35.44/14.19)	GYQGQRLSPR................itiSPA.LSQTSRVSTPR
  127-  152 (32.77/12.58)	GHASPALGPG................avaSPA.LS.TGKGNKYK
  153-  180 (29.43/10.57)	AQGSPAKLAG................srsSPAgLSQSSSPGMPP
  181-  222 (24.07/ 7.34)	TRSRP.ITPVsggssrsgtpinvqqatkiSPG.LPRASRPATPG
  223-  258 (22.56/ 6.43)	SAQASRLSPG.....vvqpggrqgagklvSPA.VME..RTKTSN
  358-  381 (26.00/ 8.51)	TQAAIAL.ES.................kiSPS.GS.SSKGGLSN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     135.69|      29|      29|     461|     489|       2
---------------------------------------------------------------------------
  405-  442 (26.86/12.16)	.VKTTAQLiaelqaksssPNLGSKTIKKIQTNQIQKEVE
  461-  489 (46.67/26.73)	SVGTPTQL..........PRVGEVTLSQTKTELVQKFLQ
  490-  515 (36.89/19.54)	SSVTPEDL..........SSPLD...SIGRTQSPANFDV
  516-  538 (25.27/10.99)	SFANSDSL..........PNSADVSLQSVKSEL......
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11953 with Med26 domain of Kingdom Metazoa
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