<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11939

Description mediator of RNA polymerase II transcription subunit 24
SequenceMTTQAGEKNMSSMKSLLMRAWRERWSDIQWGITVKRLLTRFAEAEMCNLADLILQQALVGTSPNTLVLSYLKHVQSTQIITTASVLKSVMKYEDLARPYCIKSLLELVTGMLAKISSHAYSEDSIALCKTLQQTVNWALQLAYRGLQSLQDNKQAAEYLAIVDRSCDLVAMVMKSESSKALMYIAKFEDSESARQLEQTEMNVRGVFNQLQPACITVQLKEKVEGILKGIENIYVIPTTLQPSVSMTTRSVLSTVSVMLNIEAVLNPTNDVRPIMEQLILLERAKKVERTDLYCLILRACFMGMIDSKDGTEELKWAAFTYLKLPLLFAKFSQKSPLRDCSKDLETAFEKFLNYVPLLDLTDSKCNCDCLSLFLKKLCTHGLLSDAQCKKLLAKRMKDTQKPKTPVQQNQQPSASLILRAEPTVASILKTLDADYSKSQESLLGILFHMLSGRSFELILAAAAATGKLQSFAMKMIKFNEFAKQASGDTDQAAQTTALLFDITFLMVCHIAQLYGSEIISSNIECSDSFFAQWVKRCLPEDGKAKCLDNNSFQPDPLKVESLLQQFNAGGELKTSHTKWQDVCNNIPFMVQEVLYAWEHGAIMRDTVRTMMGNIKSKLCCLPVVVVSWLCTHISSLNSTARMKPLQMIDMLQQPVVHSQTPDTANQYYSERSTLMNNIILKMAADLLPATTNKTSLSGKSDLHATLKQTFLASYRKGWLSIQALHDLEQLYCTGGAEWFCETLVKEMLQFTRVEELEHAVALVSAIFFIDMDQLTLSLLHSTLPQILQGMSFKPGIVDPRGRALIRLCVFCIGATHTMKGFPRVPSSPMKSGGKKRSRREVEIEDIEFGTGEARPSKIRKTQDEAHQQITLDAEGFNLDLIYNREETPSSPTYDVKDPLNKALAALFQLFTDIVTDSCISPKTGFVLSFLEETIHVGGDFSRFILQFMPKTMVPQLLKMLPDDFSTGFILNVCDMNSAAGRRIAAKVVSHHALYLSRQKTV
Length1001
PositionTail
OrganismLingula unguis
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Brachiopoda> Linguliformea> Lingulata> Lingulida> Linguloidea> Lingulidae> Lingula.
Aromaticity0.07
Grand average of hydropathy-0.050
Instability index49.37
Isoelectric point8.11
Molecular weight112195.32
Publications
PubMed=26383154

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11939
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     306.19|     106|     250|     363|     491|       1
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  364-  491 (143.11/132.89)	KCNCDCLSLFLKKL.CTH..GLLSDAQCKKLlakRMKDTqkPKTPVQQNQQP.SASLILRAEPTVAS..ILKtLDADY...SKSQESLlgilfhmlSGRSfELilaaaAATGKlQSFAMKMIKfNEFAKQASGDTDQ
  615-  729 (163.07/91.63)	KSKLCCLPVVVVSWlCTHisSLNSTARMKPL...QMIDM..LQQPVVHSQTPdTANQYYSERSTLMNniILK.MAADLlpaTTNKTSL........SGKS.DL.....HATLK.QTFLASYRK.GWLSIQALHDLEQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     193.97|      58|     237|       1|      60|       2
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    1-   60 (96.69/70.50)	MTTQAGEKNMSSMksLLMRAWRERWSDIQWGITVKRLLTRFAEAEMCNLADLILQQALVG
  246-  303 (97.28/64.98)	MTTRSVLSTVSVM..LNIEAVLNPTNDVRPIMEQLILLERAKKVERTDLYCLILRACFMG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.41|      23|      63|      87|     120|       6
---------------------------------------------------------------------------
   92-  115 (36.87/40.93)	YEDLaRPYCIKSLL.ELVTGMLAKI
  207-  230 (36.53/12.17)	FNQL.QPACITVQLkEKVEGILKGI
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11939 with Med24 domain of Kingdom Metazoa
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