<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11922

Description mediator of RNA polymerase II transcription subunit 24-like isoform X1
SequenceMTTQAGEKNMSSMKSLLMRAWRERWSDIQWGITVKRLLTRFAEAEMCNLADLILQQALVGTSPNTLVLSYLKHVQSTQIITTASVLKSVMKYEDLARPYCIKSLLELVTGMLAKISSHAYSEDSIALCKTLQQTVNWALQLAYRGLQSLQDNKQAAEYLGIVDRSCDLVAMVMKSESSKALMYIAKFEDSESARQLEQTEMNVRGVFNQLQPACITAQLKEKVEGILKGIENIYVIPTTSQPSVSMTTRSVLSTVSVMLNIEAVLNPTNDVRPIMEQLILLERAKKVERTDLYCLILRACFMGMIDSKDGTEELKWAAFTYLKLPLLFAKFSQKSPLRDCSKDLETAFEKFLNYVPLLDLTDSKCNCDCLSLFLKKLCTHGLLSDAQCKKLLARRMKDTQKPKTPVQQNQQPSASLILRAEPTVASILKVQLYNILQTLDADYSKSQESLLGILFHMLSGRSFELILAAAAATGKLQSFAMKMIKFNEFAKQASGDTDQAAQTTALLFDITFLMVCHIAQLYGSEIISSNIECADSFFAQWVKRCLPEDGKAKCLDNNSFQPDPLKVESLLQQFNAGGELKTSHTKWQDVCNNIPFTVQEVLYAWEHGAIMRDTVRTMMGNIKSKLCCLPVVVVSWLCTHISSLNSTARMKPLQMIDMLQQPVVHSQTPDTANQYYSERSTLMNNIILKMAADLLPATTNKTSLSGKSDLHATLKQTFLASYRKGWLSIQALHDLEQLYCTGGAEWFCETLVKEMLQFTRVEELEHAVALVSAIFFIDMDQLTLSLLHSTLPQILQGMSFKPGIVDPRGRALIRLCVFCIGATHTMKGFPRVPSSPMKSGGKKRSRREVEIEDIEFGTGEARPSKIRKTQDEAHQQITLDAEGFNLDLIYNREETPSSPTYDVKDPLNKALAALFQLFTDIVTDSCISPKTGFVLSFLEETIHVGGDFSRFILQFMPKTMVPQLLKMLPDDFSTGFILNVCDMNSAAGRRIAAKVVSHHALYLSRQKTV
Length1009
PositionTail
OrganismLingula unguis
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Brachiopoda> Linguliformea> Lingulata> Lingulida> Linguloidea> Lingulidae> Lingula.
Aromaticity0.07
Grand average of hydropathy-0.055
Instability index49.86
Isoelectric point8.11
Molecular weight113081.22
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11922
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     173.68|      45|      82|     353|     397|       1
---------------------------------------------------------------------------
   94-  131 (31.10/15.36)	......DLARPYCIKSLLELvtgMLAKISSHA....YSEDsiALCKTL......
  353-  397 (79.27/50.71)	NYVPLLDLTDSKCNCDCLSL...FLKKLCTHG....LLSD..AQCKKLLARRMK
  434-  482 (63.30/38.99)	NILQTLDADYSKSQESLLGI...LFHMLSGRSfeliLAAA..AATGKLQSFAMK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.35|      34|      80|     708|     742|       3
---------------------------------------------------------------------------
  708-  742 (57.94/46.97)	SDLHATLKQTFLA.SYRKGWLSIQ..ALHDLeQLYCTG
  785-  821 (53.41/37.87)	SLLHSTLPQILQGmSFKPGIVDPRgrALIRL.CVFCIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     223.17|      70|     242|       1|      72|       5
---------------------------------------------------------------------------
    1-   72 (116.75/81.08)	MTTQAGEKNMSSMksLLMRAWRERWSDIQWGITVKRLLTRFAEAEMCNLADLILQQALVG...TSPNT.....LVLSYLK
  246-  323 (106.42/68.10)	MTTRSVLSTVSVM..LNIEAVLNPTNDVRPIMEQLILLERAKKVERTDLYCLILRACFMGmidSKDGTeelkwAAFTYLK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11922 with Med24 domain of Kingdom Metazoa
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