<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11920

Description mediator of RNA polymerase II transcription subunit 24-like isoform X2
SequenceMTTQAGEKNMSSMKSLLMRAWRERWSDIQWGITVKRLLTRFAEAEMCNLADLILQQALVGTSPNTLVLSYLKHVQSTQIITTASVLKSVMKYEDLARPYCIKSLLELVTGMLAKISSHAYSEDSIALCKTLQQTVNWALQLAYRGLQSLQDNKQAAEYLGIVDRSCDLVAMVMKSESSKALMYIAKFEDSESARQLEQTEMNVRGVFNQLQPACITAQLKEKVEGILKGIENIYVIPTTSQPSVSMTTRSVLSTVSVMLNIEAVLNPTNDVRPIMEQLILLERAKKVERTDLYCLILRACFMGMIDSKDGTEELKWAAFTYLKLPLLFAKFSQKSPLRDCSKDLETAFEKFLNYVPLLDLTDSKCNCDCLSLFLKKLCTHGLLSDAQCKKLLARRMKDTQKPKTPVQQNQQPSASLILRAEPTVASILKTLDADYSKSQESLLGILFHMLSGRSFELILAAAAATGKLQSFAMKMIKFNEFAKQASGDTDQAAQTTALLFDITFLMVCHIAQLYGSEIISSNIECADSFFAQWVKRCLPEDGKAKCLDNNSFQPDPLKVESLLQQFNAGGELKTSHTKWQDVCNNIPFTVQEVLYAWEHGAIMRDTVRTMMGNIKSKLCCLPVVVVSWLCTHISSLNSTARMKPLQMIDMLQQPVVHSQTPDTANQYYSERSTLMNNIILKMAADLLPATTNKTSLSGKSDLHATLKQTFLASYRKGWLSIQALHDLEQLYCTGGAEWFCETLVKEMLQFTRVEELEHAVALVSAIFFIDMDQLTLSLLHSTLPQILQGMSFKPGIVDPRGRALIRLCVFCIGATHTMKGFPRVPSSPMKSGGKKRSRREVEIEDIEFGTGEARPSKIRKTQDEAHQQITLDAEGFNLDLIYNREETPSSPTYDVKDPLNKALAALFQLFTDIVTDSCISPKTGFVLSFLEETIHVGGDFSRFILQFMPKTMVPQLLKMLPDDFSTGFILNVCDMNSAAGRRIAAKVVSHHALYLSRQKTV
Length1001
PositionTail
OrganismLingula unguis
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Brachiopoda> Linguliformea> Lingulata> Lingulida> Linguloidea> Lingulidae> Lingula.
Aromaticity0.07
Grand average of hydropathy-0.060
Instability index49.31
Isoelectric point8.11
Molecular weight112109.08
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11920
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     575.67|     175|     249|     363|     556|       1
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  166-  243 (57.42/18.20)	....CDLVAM.VMKSESSK..ALMYIAKFEdSESARQLEQTEMNVRGVFNQLQP..ACITAQLKEKVEG..ILKGIENIYvipTTSQPS..........................................................................................................................
  363-  556 (268.19/157.29)	SKCnCDCLSL.FLKKLCTH..GLLSDAQCK.KLLARRMKDTQKPKTPVQQNQQP.SASLILRAEPTVAS..ILKTLDADY...SKSQESLlgilfhmlSGRSfELilaaaAATGKlQSFAMKMIKfNEFAKQASGDTDQAAQT.TALLFDITflMVCHIAQLYGSEIISSNIECADS.FFAQWVKRCLP..EDGKAKCLDNNSFQP...DP
  616-  799 (250.06/114.50)	SKL.C.CLPVvVVSWLCTHisSLNSTARMK.PL...QMIDML..QQPVVHSQTPdTANQYYSERSTLMNniILK.MAADLlpaTTNKTSL........SGKS.DL.....HATLK.QTFLASYRK.GWLSIQALHDLEQLYCTgGAEWFCET..LVKEMLQFTRVEELEHAVALVSAiFFIDMDQLTLSllHSTLPQILQGMSFKPgivDP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     223.17|      70|     248|       1|      72|       2
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    1-   72 (116.75/82.37)	MTTQAGEKNMSSMksLLMRAWRERWSDIQWGITVKRLLTRFAEAEMCNLADLILQQALVG...TSPNT.....LVLSYLK
  246-  323 (106.42/69.17)	MTTRSVLSTVSVM..LNIEAVLNPTNDVRPIMEQLILLERAKKVERTDLYCLILRACFMGmidSKDGTeelkwAAFTYLK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11920 with Med24 domain of Kingdom Metazoa
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