<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11913

Description mediator of RNA polymerase II transcription subunit 25 isoform X7
SequenceMVAGFSGQDPVSDVVLVVEATANLGAYFDDLLKSYVLPTLEHFDGGPPSEIDYGFDYNCTLYSLVMFGAADCGPDPAARCRAPTTSTSELLSWIDGVQFVGGGGEERSFVAEGLSTALQIFDDYNKVRDQNTQTNKYCILVCNSPPYQIPSQESIKYSGYNAEDLAHMMGQRGINLSVISPRKIPSLCRLYDKANHDHSPPKDYTIDPRHLVLLRGYSLQERPPSPGGDKIQDKSIQKLPAKVGSPAAGSETSSAPGPPHISSGPGTMLQQHPTSIAPPASQPTSAASGMGLQRHPPPNVLASTQAQQLTTTLKGQNAKEVTKMILEQTKPGNIRPSSQFTQQLQQQQQQQQGMQPGPGPPLSQQPGLHMPPVSQPLPMASYQSQLPTQSQPTTSLTSATGMGTVMSSQASHQNFQGGGMKAPPQQGGMMVGGGQSGMMTSQPNMMTPQQQQHMMTSQSNLMSSQASNMMMTSSQSNIMPSSQPNLMSSQMNMGNSQISQPGMMSTQGGMMTSQQQQQQPQQPGGPQNVMVSQQNMMAQSQNNMMPAQNNMGPSQSDMMTQGGMYQNPNMQSGLRNPGPPQSRMPMQSNVQPGVPMGQMANQPLDMLMAGPGGGLLDNPASRAGAKDLWTGALEWQEKTKTGNTTDPGAKIIRSLPCKVYITQGEQEVNASIWPNKLQMQLIPQAILQSLQSLFRNSRTVSFQFANTDKEAIKSLYKILSQGFAGYIHFPTMSQVDVRVVLLLYSTKMKKFVGLIPNDQNSFINGIKIAVTKHKTMQQMKMQQQLQQRGMMNQMAGGVQQPPQSQPGMQTPQQPLLGQNSQFSQAATLTTQQQQQLQPQQQSQQVAQQPQSQQSQMMGQADQFNPSGPMPGPGPQQPQQRIPATMMGGPPLPGPPAVGPPSVPSGMMGPQQVSNVNQMGMAGGGLTISDQERQANLSTIPMLQRALAAAQAKEKQFQTQRQIDEARAQHTLVQQRQQQLQQVQQQQQRLQLQQQQQQQQQQQNPSNPQLKQILINQQQQQAQQQRLHQQQLLMQQQQQQQQQQLPRGPGPQGMGQGMGQPGMQQSGMGQMGQLGQSQPFGDGFDLESLL
Length1089
PositionUnknown
OrganismLingula unguis
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Brachiopoda> Linguliformea> Lingulata> Lingulida> Linguloidea> Lingulidae> Lingula.
Aromaticity0.04
Grand average of hydropathy-0.698
Instability index68.07
Isoelectric point8.97
Molecular weight118372.62
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11913
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     401.62|      39|      39|     969|    1007|       1
---------------------------------------------------------------------------
  350-  384 (50.05/ 8.70)	QQQGMQPG..PGP...P.L..SQQPGLHMPPVS...QPLPMASYQS
  432-  470 (49.79/ 8.60)	GGGQSGMM..TSQ...PNM..MTPQQQQHMMTSQSNLMSSQASNMM
  562-  600 (48.01/ 7.93)	GGMYQ.NP..NMQ...SGLrnPGPPQSRMPMQSNVQPGVPMG.QMA
  796-  833 (55.35/10.69)	GGV.QQPP..QSQ...PGM..QTPQQPLLGQNSQFSQAATLTTQQQ
  858-  892 (44.44/ 6.58)	GQADQFNP..SGP.mpGPG..PQQPQQRIPATMMGGPPL......P
  964-  996 (45.66/ 7.04)	EARAQ...........HTL..VQQRQQQLQQVQQQQQRLQLQQQQQ
  997- 1037 (54.15/10.24)	QQQQQQNP..SNPqlkQIL..INQQQQQAQQQRLHQQQL.LMQQQQ
 1038- 1077 (54.17/10.25)	QQQQQQLPrgPGP...QGM..GQGMGQPGMQQSGMGQMGQLGQSQ.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.95|      30|      55|     474|     507|       2
---------------------------------------------------------------------------
  474-  507 (51.64/20.02)	SQSNIMPSSQPNLMSSQMNMGNsqiSQPGMMsTQ
  532-  561 (55.31/15.15)	SQQNMMAQSQNNMMPAQNNMGP...SQSDMM.TQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     230.07|      42|      54|     144|     185|       3
---------------------------------------------------------------------------
  144-  185 (73.29/42.49)	SPP..YQIPS....QESIKYSGYNAEDLAHMMGQRGINLSVISPRKI.P
  199-  240 (58.27/31.85)	SPPkdYTIDP....RHLVLLRGYSLQERPPSPGGDKIQDKSI..QKL.P
  250-  283 (53.96/28.80)	SET..SSAPG....PPHIS.SGPGT.....MLQQH..PTSIAPPASQ.P
  296-  336 (44.56/22.13)	PPP..NVLAStqaqQLTTTLKGQNAKEVTKMI......LEQTKPGNIrP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.96|      25|      37|     611|     647|       6
---------------------------------------------------------------------------
  611-  636 (40.61/49.88)	PGGGLLDNPASRAGAkDLWTGALEWQ
  656-  680 (45.35/23.37)	PCKVYITQGEQEVNA.SIWPNKLQMQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.05|      15|      21|     688|     705|      11
---------------------------------------------------------------------------
  688-  705 (20.36/24.89)	QSLQSLFrnsRTVSFQFA
  710-  724 (24.70/18.09)	EAIKSLY...KILSQGFA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.59|      17|     150|     753|     769|      12
---------------------------------------------------------------------------
  753-  769 (29.12/13.89)	GLIPNDQNSFINGIKIA
  905-  921 (30.48/14.90)	GMMGPQQVSNVNQMGMA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11913 with Med25 domain of Kingdom Metazoa
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