<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11901

Description mediator of RNA polymerase II transcription subunit 24 isoform X2
SequenceMGMKMVSYSSVLTAISKFDDFSRDLCVQALLDIMNMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERIQEGLEAGTPASGEKQLAMCLQCLEKTLSSTKNRALLHIAKLEEASSWTAIEHSLLKLGEILTSLNSPQLRSQAEKCGTLIRSIPTMLSVHSEKLHKTGFPTVHALILLEGTMNLTGETQPLVEQLMMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTQELKWTAFTYLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCTNFLLQECNKQGLLSEANFANLVAKRAADRDPELKSSENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTHGSGESTKTASVRALLFDISFLMLCHVAQTYGSEVILSESSTGAEVPFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLYSENTLQFYKERVVIMSSILEHMCADVLQQTATQIKFPSAGVDTMPYWNLLPPKRPIKEVLMDIFAKVLEKGWVDSRSIHILDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSAKWQNLMDPPGTALAKLAVWCALSSYSSHKGQASSRQKKRHREDIEDYISLFPLEDTQPSKLMRLLSSTEDDANLLSSPTDRSMNTSLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGSQGSILQFMPFTTVSELVKVSAMSSPKVVLAITDLSLPLGRQVAAKAIAAL
Length920
PositionTail
OrganismDipodomys ordii (Ord's kangaroo rat)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Castorimorpha> Heteromyidae> Dipodomyinae> Dipodomys.
Aromaticity0.06
Grand average of hydropathy0.032
Instability index44.94
Isoelectric point6.29
Molecular weight102117.78
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11901
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     125.57|      39|      68|     412|     453|       1
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  412-  453 (59.77/44.05)	ESTKTASVRALLFDISFLMLChvaQTYGSEVILSESSTGAEV
  481-  519 (65.80/40.66)	DSTKVESLVALLNNSSEMKLV...QMKWHEACLSISAAILEI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     116.57|      25|      69|      25|      49|       3
---------------------------------------------------------------------------
   25-   49 (45.69/26.90)	LCVQALLDIMNMFCDRLSCH.GKAEE
   53-   73 (35.05/18.92)	LC.RALLSALHWL...LRCT.AASAE
   93-  118 (35.83/19.51)	MCLQCLEKTLSSTKNRALLHiAKLEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.18|      20|     130|     210|     232|       5
---------------------------------------------------------------------------
  210-  232 (33.18/34.84)	PTplfVLEIWKACFVGLIESPEG
  346-  365 (37.00/27.20)	PT...VTNILKTMDADHSKSPEG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     164.95|      53|     117|     547|     607|       7
---------------------------------------------------------------------------
  547-  603 (78.12/67.47)	LAVCAVAWLVAHV..RMLGLDEREKSLQMIrQLagpLYSENTLQFYKERVVIMSSILEH
  667-  721 (86.83/52.60)	LHMGGVYWFCNNLikELLKETRKEHTLRAV.EL...LYSIFCLDMQQVTLVLLGHILPG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11901 with Med24 domain of Kingdom Metazoa
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