<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11881

Description mediator of RNA polymerase II transcription subunit 25 isoform X1
SequenceMVPGSEGPARAGGLVADVVFVIEGTANLGPYFEGLRNHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLDGIRFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTESLVQKIGERGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQPPADVSQDPRHMVLVRGLVLPVGGSSAAGPLQPKQPVPLPPAPSSAATLSTAPQQALPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPINPLQQAASGVGPPFSQAPASTLPQGPPGAPKPPPSSQPSLVSTVAPGPGLAPPAPSGAASMAGSVAPGGVSGPSPAQMGAPALGGQQSVPNKLLAWSGVLEWQEKPKPASVDASTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFNKDQESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGMGAQQAPPGLGPILEDQARPPQNLLQLRAPQPQPQATVGASGAAGQPQPQSTTQAPPGAPQGPPGAAPGPPPPGPTLRPQNPGANPQLRSLLLNPPPPQSGVPLPQASLHHLQPPGAPALLPPPHQSLGQPQLGPPLLHPPPAQSWPAQLPPRAPLPVAKRKREGEGRVFRERWERDYFFVEVKNMPTCLICKKIVSVLKEYNLKRHYESQHSKSYSQYTEQTRAAILSELKKGLKCQ
Length794
PositionUnknown
OrganismDipodomys ordii (Ord's kangaroo rat)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Castorimorpha> Heteromyidae> Dipodomyinae> Dipodomys.
Aromaticity0.06
Grand average of hydropathy-0.311
Instability index60.89
Isoelectric point9.27
Molecular weight84341.78
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11881
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     190.63|      37|      38|     585|     622|       2
---------------------------------------------------------------------------
  327-  355 (44.58/ 8.32)	TlPQGPPG........AP....KPPP.........SSQPSLVSTV.APgPG
  357-  404 (45.24/ 8.55)	A.PPAPSGAasmagsvAPggvsGPSP.AQMGAPALGGQQSVPNKLLAW.SG
  583-  614 (48.27/11.92)	.......LR.......AP....QPQPqATVGASGAAGQPQPQSTTQAP.PG
  615-  640 (52.54/11.11)	A.PQGPPGA.......AP....GPPP............PGPTLRPQNP.GA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     154.00|      25|      42|     641|     665|       3
---------------------------------------------------------------------------
  215-  252 (28.63/ 6.02)	QdPRhmvlVRGLVLPvggssaagPLQPKQ...PVP..LPPAPS
  260-  283 (34.52/ 8.91)	A.PQ.......QALP........PVPPQY...QVPgnLSAAQV
  641-  665 (49.07/16.04)	N.PQ....LRSLLLN........PPPPQS...GVP..LPQASL
  686-  712 (41.78/12.46)	Q.PQ....LGPPLLH........PPPAQSwpaQLP...PRAPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.92|      30|     111|      39|      69|       4
---------------------------------------------------------------------------
   39-   69 (53.43/38.00)	YLLPAIEYFN.GGPPAETdFGGDYG..GTQYSLV
  151-  183 (44.49/26.22)	YLLPAVESTTySGCTTES.LVQKIGerGIHFSIV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.35|      23|     257|     289|     324|       5
---------------------------------------------------------------------------
  294-  324 (37.18/19.81)	NQKAGLGPrfspinplQQAASGVGPPFS.QA.P
  552-  576 (37.17/ 8.36)	EQQRGMGA........QQAPPGLGPILEdQArP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11881 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GPLQPKQPVPLPPAPSSAATLSTAPQQALPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPINPLQQAASGVGPPFSQAPASTLPQGPPGAPKPPPSSQPSLVSTVAPGPGLAPPAPSGAASMAGSVAPGGVSGPSPAQMGAPALGGQQ
2) HKQVQQQKLEQQRGMGAQQAPPGLGPILEDQARPPQNLLQLRAPQPQPQATVGASGAAGQPQPQSTTQAPPGAPQGPPGAAPGPPPPGPTLRPQNPGANPQLRSLLLNPPPPQSGVPLPQASLHHLQPPGAPALLPPPHQSLGQPQLGPPLLHPPPAQSWPAQLPPRAPLPVAKRKREGEG
237
543
393
723










Molecular Recognition Features






MoRF SequenceStartStop




NANANA