<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11880

Description mediator of RNA polymerase II transcription subunit 23 isoform X5
SequenceMETQLQSIFEEVVKTEIIEEAFPGMFMDTPEDEKTKLISCLSAFRQFWNGLSQESHEQCIQWIVKFIHGQHSPKRISFLYDCLAMAVETGVLPPRIVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAKEVIAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPATLRFPLKGLLPYDKQKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAQNGDSNLQIPIPHSLKLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMKIPLPGTSCLASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHTKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTDQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMNFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMTNENDIITQFSVQGFPPLFLCLLWKMLLETDHISQIGYRVLDRIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVNDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMYLRKRDHLKRKLVHAIIGSLKDNRPQGWCLSDTYLKNAMNAREDNPWVPEDSYYCKLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKDVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSNSLTSETEWVGYPFRLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEYQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHISKLEPAAVPQPAVNSGSPAPQSTQVPAPLPVTQ
Length1336
PositionTail
OrganismDipodomys ordii (Ord's kangaroo rat)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Castorimorpha> Heteromyidae> Dipodomyinae> Dipodomys.
Aromaticity0.10
Grand average of hydropathy-0.005
Instability index45.16
Isoelectric point7.07
Molecular weight152602.66
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11880
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     145.08|      45|     178|     651|     700|       1
---------------------------------------------------------------------------
  651-  700 (74.01/54.76)	LNRaLILTLARATHVTD.....FFTgsdsIQGTWCK..DILQTIMNFTPHNWASHTL
  830-  881 (71.07/40.23)	LDR.LILCLAMRSHEGNeaqvcYFI....IQLLLLKpnDFRNRVNDFVKENSPEHWL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     164.62|      47|     371|     882|     932|       2
---------------------------------------------------------------------------
  189-  228 (34.60/18.25)	.................KLYP..EGklphwlLGNLVSDFVDTFRPTARI..NSICGRcsLL
  232-  267 (49.42/29.94)	NNSGAI..CNSWKLDPATLRFplKG......LL.....PYDKQKQRCPV............
  882-  932 (80.60/69.86)	QNDWHTkhMNYHKKYPEKLYF..EG......LAEQVDPPVQIQSPYLPIyfGNVCLR..FL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     109.51|      34|      81|     346|     380|       3
---------------------------------------------------------------------------
  346-  380 (56.13/37.76)	QFISGSIQKNAL..ADFlPVMKLFDLLYPEKECIPVP
  424-  459 (53.38/31.46)	EFLQQSLRNKSLqmNDY.KIALLCNAYSTNSECFTLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     114.36|      35|     648|     298|     340|       5
---------------------------------------------------------------------------
  298-  340 (52.36/56.04)	LWQHLSSqliffvLFQFASFPhmVLSLHQKLAGRGL.IKGRDHL
  955-  990 (62.00/41.93)	LLDHLGG......LYKFHDRP..VTYLYNTLHYYEMyLRKRDHL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     147.76|      46|     256|     490|     541|       6
---------------------------------------------------------------------------
  490-  541 (66.59/60.33)	PLPMNLLDSLTVHAKMslIHSIATRVIKLAHTKSSValapALVETYSRLLVY
  755-  800 (81.18/55.54)	PLFLCLLWKMLLETDH..ISQIGYRVLDRIGARALV....AHVRTFADFLVY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.75|      15|     368|     558|     576|       8
---------------------------------------------------------------------------
  558-  572 (27.74/25.74)	PTVFKSHAWGILHTL
  584-  598 (27.01/12.01)	QPHYRVQLLSHLHTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.23|      18|     685|      39|      56|      12
---------------------------------------------------------------------------
   39-   56 (34.20/23.52)	SCLSA.FRQFW..NGLSQESH
  701-  721 (23.03/13.09)	SCFPApLQAFFkqNNVPQESR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.60|      12|     255|     939|     950|      15
---------------------------------------------------------------------------
  939-  950 (22.31/12.27)	IHRFLE..LLPVSK
 1195- 1208 (17.30/ 7.81)	IPKFLTevLLPIVK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11880 with Med23 domain of Kingdom Metazoa
Unable to open file!