<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11879

Description mediator of RNA polymerase II transcription subunit 23 isoform X2
SequenceMETQLQSIFEEVVKTEIIEEAFPGMFMDTPEDEKTKLISCLSAFRQFWNGLSQESHEQCIQWIVKFIHGQHSPKRISFLYDCLAMAVETGVLPPRIVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAKEVIAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQQKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAQNGDSNLQIPIPHSLKLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMKIPLPGTSCLASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHTKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTDQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMNFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMTNENDIITQFSVQGFPPLFLCLLWKMLLETDHISQIGYRVLDRIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVNDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMYLRKRDHLKRKLVHAIIGSLKDNRPQGWCLSDTYLKNAMNAREDNPWVPEDSYYCKLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKDVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSNSLTSETEWVGYPFRLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEYQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHISKLEPAAVPQPAVNSGSPAPQSTQVPAPLPVTQ
Length1368
PositionTail
OrganismDipodomys ordii (Ord's kangaroo rat)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Castorimorpha> Heteromyidae> Dipodomyinae> Dipodomys.
Aromaticity0.10
Grand average of hydropathy-0.012
Instability index45.44
Isoelectric point6.98
Molecular weight156371.00
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11879
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     149.50|      46|     256|     971|    1016|       1
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  971- 1016 (85.05/50.83)	IHRFLE..LLPVSKSLETLL..DHLGG..LYKF.HDRPVTYLYNTLHYYEMYL
 1227- 1279 (64.45/36.77)	IPKFLTevLLPIVKTEYQLLyvYHLVGpfLQRFqQERTRCMIEIGVAFYDMLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     374.80|     119|     256|     220|     349|       2
---------------------------------------------------------------------------
  220-  349 (186.81/160.89)	SICGRCSLLPVvnnsGAICNSwKLDPATLRFPLKG........LLPYDKDLFEPQTALLRYVLEQPYSRDMVcnMLGLNKQQKQRCPVLEDQLVDLVVYAmersETEEKFDDGGTSQLLWQHLSSQL..IFFVLFQFASF
  482-  610 (187.98/129.62)	STNSECFTLPM....GALVET.IYGNGIMKIPLPGtsclasgsITPLPMNLLDSLTVHAKMSLIHSIATRVI..KLAHTKSSVALAPALVETYSRLLVYM....EIESLGIKGFISQLLPTVFKSHAwgILHTLLEMFSY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.35|      28|     711|      29|      56|       3
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   29-   56 (51.89/36.83)	TPEDEKTKLISCLSA.FRQFW..NGLSQESH
  723-  753 (45.46/31.21)	TPHNWASHTLSCFPApLQAFFkqNNVPQESR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     130.72|      40|     365|     914|     964|      11
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  916-  964 (67.95/61.21)	DWHTKHMN.........YHKKYpeklYFEG..LAEQVDPPVQIQSPYLPIYfgnvcLRFL
 1282- 1332 (62.76/31.85)	DQCSTHLNymdpicdflYHMKY....MFTGdsVKEQVEKIICNLKPALKLR.....LRFI
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11879 with Med23 domain of Kingdom Metazoa
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