<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP11875

Description mediator of RNA polymerase II transcription subunit 23 isoform X4
SequenceMETQLQSIFEEVVKTEIIEEAFPGMFMDTPEDEKTKLISCLSAFRQFWNGLSQESHEQCIQWIVKFIHGQHSPKRISFLYDCLAMAVETGVLPPRIVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAKELLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQTLNIAQQKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAQNGDSNLQIPIPHSLKLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMKIPLPGTSCLASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHTKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTDQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMNFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMTNENDIITQFSVQGFPPLFLCLLWKMLLETDHISQIGYRVLDRIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVNDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMYLRKRDHLKRKLVHAIIGSLKDNRPQGWCLSDTYLKNAMNAREDNPWVPEDSYYCKLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKDVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSNSLTSETEWVGYPFRLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEYQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHISKLEPAAVPQPAVNSGSPAPQSTQVPAPLPVTQ
Length1340
PositionTail
OrganismDipodomys ordii (Ord's kangaroo rat)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Castorimorpha> Heteromyidae> Dipodomyinae> Dipodomys.
Aromaticity0.10
Grand average of hydropathy-0.017
Instability index45.04
Isoelectric point6.89
Molecular weight153041.05
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP11875
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     215.31|      52|      95|    1037|    1088|       1
---------------------------------------------------------------------------
  781-  823 (45.81/24.17)	.........RVLDRIGARALvahvRTFA..DF.....LVYEFSTSAGGQQLNKCIEI..LN
 1037- 1088 (92.51/56.37)	DSYYCKLIGRLVDTMAGKSP....GPFPNCDW.....RFNEFPNPAAHALHVTCVELMALA
 1130- 1184 (76.99/45.67)	EPYWIVLHDRIVSVISSNSL....T..SETEWvgypfRLFDFTACHQSYSEMSCSYTLALA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      92.67|      19|      95|     881|     899|       2
---------------------------------------------------------------------------
  881-  899 (40.52/25.94)	PEHWLQNDWHTKH.MNYHKK
  973-  991 (33.36/19.98)	PVTYLYNTLHYYE.MYLRKR
 1011- 1026 (18.79/ 7.86)	PQGWCLSDTYLKNaMN....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     158.49|      35|      81|     350|     384|       4
---------------------------------------------------------------------------
  350-  384 (59.72/34.47)	QFISGSIQKNAL..ADFLPVMKLF...DLLYPEKECIPVP
  428-  463 (50.09/27.75)	EFLQQSLRNKSLqmNDY.KIALLC...NAYSTNSECFTLP
  676-  710 (48.68/26.76)	...SDSIQGTWC..KDILQTIMNFtphNWASHTLSCFPAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.96|      12|      44|     203|     214|       6
---------------------------------------------------------------------------
  203-  214 (23.75/14.62)	ICNSWKLDPATL
  249-  260 (22.22/13.19)	VCNMLGLNKQTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     202.84|      69|      81|     488|     565|       7
---------------------------------------------------------------------------
  472-  551 (80.57/73.19)	YGNGIMKIPLPGTscLASGSITPLpMNLLDSLTVhaKMSLIHSiATRVIKLAHTKSsvaLApALVETYSRLLvYMEIESL
  552-  620 (122.27/71.30)	GIKGFISQLLPTV..FKSHAWGIL.HTLLEMFSY..RMHHIQP.HYRVQLLSHLHT...LA.AVAQTDQNQL.HLCVEST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.34|      13|     649|     302|     318|      10
---------------------------------------------------------------------------
  272-  284 (21.27/ 9.37)	LEDQLVDLVVYAM
  306-  318 (22.08/ 6.46)	LSSQLIFFVLFQF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      97.81|      21|     301|     949|     969|      12
---------------------------------------------------------------------------
  949-  969 (36.10/20.89)	LLPVSKSLETLL..DHLGG..LYKF
 1207- 1231 (26.09/13.03)	LLPIVKTEYQLLyvYHLVGpfLQRF
 1250- 1269 (35.62/20.52)	LLNVDQC.STHL..NYMDP..ICDF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP11875 with Med23 domain of Kingdom Metazoa
Unable to open file!